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Cox18 Gene Detail
Summary
  • Symbol
    Cox18
  • Name
    cytochrome c oxidase assembly protein 18
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448532
    NCBI Gene: 231430
Location & Maps
more
  • Sequence Map
    Chr5:90214724-90224001 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9278 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 44.32 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    COX18, COX18, cytochrome c oxidase assembly factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COX18, COX18, cytochrome c oxidase assembly factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COX18HS
  • Links
    NCBI Gene ID: 285521
    neXtProt AC: NX_Q8N8Q8

  • Chr Location
    4q13.3; chr4:73054696-73069759 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Gene trapped
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Genomic Mutations
    4 involving Cox18
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027846 VEGA Gene Model | MGI Sequence Detail 9278 C57BL/6J ±  kb
transcript OTTMUST00000068948 VEGA | MGI Sequence Detail 1307 Not Applicable  
polypeptide OTTMUSP00000034959 VEGA | MGI Sequence Detail 332 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    114 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000005774 mitochondrial inner membrane protein COX18
  • InterPro Domains
    IPR001708 Membrane insertase OXA1/ALB3/YidC
Molecular
Reagents
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  • All nucleic 37
    Genomic 1
    cDNA 36

    Microarray probesets 5
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory