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Vps13d Gene Detail
Summary
  • Symbol
    Vps13d
  • Name
    vacuolar protein sorting 13D
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448530
    NCBI Gene: 230895
  • Gene Overview
    MyGene.info: VPS13D
Location & Maps
more
  • Sequence Map
    Chr4:144972622-145195005 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      222384 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 78.17 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    VPS13D, vacuolar protein sorting 13 homolog D
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VPS13D, vacuolar protein sorting 13 homolog D
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 55187
    neXtProt AC: NX_Q5THJ4

  • Chr Location
    1p36.22; chr1:12230039-12512047 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    44
  • Chemically induced (other)
    1
  • Gene trapped
    39
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    2 involving Vps13d
  • Incidental Mutations
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010745 VEGA Gene Model | MGI Sequence Detail 222384 C57BL/6J ±  kb
transcript OTTMUST00000025098 VEGA | MGI Sequence Detail 15849 Not Applicable  
polypeptide OTTMUSP00000011502 VEGA | MGI Sequence Detail 4390 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1867 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR009060 UBA-like
    IPR015940 Ubiquitin-associated domain
    IPR026847 Vacuolar protein sorting-associated protein 13
    IPR031645 Vacuolar protein sorting-associated protein 13, C-terminal
    IPR026854 Vacuolar protein sorting-associated protein 13, N-terminal domain
    IPR031646 Vacuolar protein sorting-associated protein 13, second N-terminal domain
    IPR009543 Vacuolar protein sorting-associated protein 13, SHR-binding domain
    IPR031642 VPS13, repeated coiled region
Molecular
Reagents
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  • All nucleic 14
    cDNA 14

    Microarray probesets 7
Other
Accession IDs
less
MGI:2140701
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory