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Gmps Gene Detail
Summary
  • Symbol
    Gmps
  • Name
    guanine monophosphate synthetase
  • Synonyms
    Gm9479
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448526
    NCBI Gene: 229363
  • Gene Overview
    MyGene.info: GMPS
Location & Maps
more
  • Sequence Map
    Chr3:63976106-64022579 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46474 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 30.08 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GMPS, guanine monophosphate synthase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GMPS, guanine monophosphate synthase
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8833
    neXtProt AC: NX_P49915

  • Chr Location
    3q24; chr3:155869430-155939608 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Gmps
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031018 VEGA Gene Model | MGI Sequence Detail 46474 C57BL/6J ±  kb
transcript OTTMUST00000076838 VEGA | MGI Sequence Detail 8105 Not Applicable  
polypeptide OTTMUSP00000040514 VEGA | MGI Sequence Detail 693 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    51 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008079 GMP synthase [glutamine-hydrolyzing]
  • EC
  • InterPro Domains
    IPR029062 Class I glutamine amidotransferase-like
    IPR017926 Glutamine amidotransferase
    IPR001674 GMP synthase, C-terminal
    IPR004739 GMP synthase, glutamine amidotransferase
    IPR025777 GMP synthetase ATP pyrophosphatase domain
    IPR022310 NAD/GMP synthase
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Molecular
Reagents
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  • All nucleic 17
    cDNA 17

    Microarray probesets 6
Other
Accession IDs
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MGI:3034331, MGI:3034880, MGI:3779888
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory