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Gmps
Gene Detail
Symbol

Name
ID
Gmps
guanine monophosphate synthetase
MGI:2448526
Synonyms
Gm9479
Feature Type
protein coding gene
Genetic Map
Chromosome 3
30.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:63976106-64022579 bp, + strand
From VEGA annotation of GRCm38

  46474 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68367  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: GMP synthase (glutamine-hydrolyzing)
Gene Tree: Gmps

Human
homologs
Human Homolog GMPS, guanine monphosphate synthase
NCBI Gene ID 8833
neXtProt AC  NX_P49915
Human Chr (Location)  3q24; chr3:155870536-155937732 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(6)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gmps interacts with 489 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process glutamine metabolic process, GMP biosynthetic process, ...
Component cytoplasm, cytosol
Function ATP binding, GMP synthase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (97)    Tissues (97)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 97
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000031018 (Evidence)
Ensembl Gene ModelENSMUSG00000027823 (Evidence)
Entrez Gene229363 (Evidence)
DFCITC1679708, TC1622865, TC1606117
DoTSDT.111048615, DT.60103478, DT.97349777
NIA Mouse Gene IndexU042433
EC6.3.5.2
Consensus CDS ProjectCCDS17383.1
International Mouse Knockout Project StatusGmps
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031018 VEGA Gene Model | MGI Sequence Detail 46474 C57BL/6J ±  kb
transcript OTTMUST00000076838 VEGA | MGI Sequence Detail 8105 Not Applicable 
polypeptide OTTMUSP00000040514 VEGA | MGI Sequence Detail 693 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(54 from dbSNP Build 137)    SNPs within 2kb including multiple locations(60)
Protein-related
information
ResourceIDDescription
InterPro IPR017926 Glutamine amidotransferase
InterPro IPR001674 GMP synthase, C-terminal
InterPro IPR004739 GMP synthase, N-terminal
InterPro IPR025777 GMP synthetase ATP pyrophosphatase domain
InterPro IPR022310 NAD/GMP synthase
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000008079 GMP synthase [glutamine-hydrolyzing]
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
All references(35)
Other
accession IDs
MGI:3034331, MGI:3034880, MGI:3779888

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory