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Gmps Gene Detail
Summary
  • Symbol
    Gmps
  • Name
    guanine monophosphate synthetase
  • Synonyms
    Gm9479
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448526
    NCBI Gene: 229363
  • Gene Overview
    MyGene.info: GMPS
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:63976106-64022579 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 30.08 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448526
protein coding gene Chr3:63964819-64022579 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027265
protein coding gene Chr3:63024287-63087543 (+)
A/J MGP_AJ_G0027225
protein coding gene Chr3:61139562-61199290 (+)
AKR/J MGP_AKRJ_G0027195
protein coding gene Chr3:62360948-62423520 (+)
BALB/cJ MGP_BALBcJ_G0027238
protein coding gene Chr3:60913667-60956224 (+)
C3H/HeJ MGP_C3HHeJ_G0026981
protein coding gene Chr3:62597643-62654598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027684
protein coding gene Chr3:65329028-65377933 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025038
protein coding gene Chr3:57642686-57683918 (+)
CAST/EiJ MGP_CASTEiJ_G0026433
protein coding gene Chr3:62732190-62797724 (+)
CBA/J MGP_CBAJ_G0026957
protein coding gene Chr3:67436096-67493159 (+)
DBA/2J MGP_DBA2J_G0027091
protein coding gene Chr3:60554893-60605388 (+)
FVB/NJ MGP_FVBNJ_G0027059
protein coding gene Chr3:59359952-59407549 (+)
LP/J MGP_LPJ_G0027202
protein coding gene Chr3:63872035-63924434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027076
protein coding gene Chr3:71908890-71970764 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027742
protein coding gene Chr3:62291315-62436367 (+)
PWK/PhJ MGP_PWKPhJ_G0026165
protein coding gene Chr3:60138238-60216677 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025978
protein coding gene Chr3:61822226-61868507 (+)
WSB/EiJ MGP_WSBEiJ_G0026507
protein coding gene Chr3:62426219-62482408 (+)



Homology
more
  • Human Ortholog
    GMPS, guanine monophosphate synthase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GMPS, guanine monophosphate synthase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GATD7
  • Links
    NCBI Gene ID: 8833
    neXtProt AC: NX_P49915
    UniProt: P49915

  • Chr Location
    3q25.31; chr3:155869430-155943679 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027823 Ensembl Gene Model | MGI Sequence Detail 46474 C57BL/6J ±  kb
transcript ENSMUST00000029405 Ensembl | MGI Sequence Detail 8105 Not Applicable  
polypeptide ENSMUSP00000029405 Ensembl | MGI Sequence Detail 693 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:3034331, MGI:3034880, MGI:3779888
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:240192 Holzer K, et al., Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer. Am J Pathol. 2017 Feb;187(2):228-235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory