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Pip5kl1 Gene Detail
Summary
  • Symbol
    Pip5kl1
  • Name
    phosphatidylinositol-4-phosphate 5-kinase-like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448520
    NCBI Gene: 227733
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32575163-32583782 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 22.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448520
protein coding gene Chr2:32574797-32583782 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025612
protein coding gene Chr2:31049241-31059812 (+)
A/J MGP_AJ_G0025589
protein coding gene Chr2:29722126-29731122 (+)
AKR/J MGP_AKRJ_G0025559
protein coding gene Chr2:30787199-30797835 (+)
BALB/cJ MGP_BALBcJ_G0025586
protein coding gene Chr2:29847518-29856893 (+)
C3H/HeJ MGP_C3HHeJ_G0025346
protein coding gene Chr2:30676890-30685900 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026030
protein coding gene Chr2:31989929-32001762 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023439
protein coding gene Chr2:28442158-28451085 (+)
CAST/EiJ MGP_CASTEiJ_G0024808
protein coding gene Chr2:30616035-30626541 (+)
CBA/J MGP_CBAJ_G0025324
protein coding gene Chr2:33207213-33219378 (+)
DBA/2J MGP_DBA2J_G0025457
protein coding gene Chr2:29490423-29499154 (+)
FVB/NJ MGP_FVBNJ_G0025419
protein coding gene Chr2:29365432-29374777 (+)
LP/J MGP_LPJ_G0025543
protein coding gene Chr2:30925010-30935494 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025450
protein coding gene Chr2:32840126-32849106 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026088
protein coding gene Chr2:30665822-30674805 (+)
PWK/PhJ MGP_PWKPhJ_G0024556
protein coding gene Chr2:29395531-29405319 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024356
protein coding gene Chr2:30820546-30829436 (+)
WSB/EiJ MGP_WSBEiJ_G0024877
protein coding gene Chr2:30842182-30852210 (+)



Homology
more
  • Human Ortholog
    PIP5KL1, phosphatidylinositol-4-phosphate 5-kinase like 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PIP5KL1, phosphatidylinositol-4-phosphate 5-kinase like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PIPKH
  • Links
    NCBI Gene ID: 138429
    neXtProt AC: NX_Q5T9C9
    UniProt: Q5T9C9

  • Chr Location
    9q34.11; chr9:127920886-127931958 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 227733 NCBI Gene Model | MGI Sequence Detail 8620 C57BL/6J ±  kb
transcript NM_198191 RefSeq | MGI Sequence Detail 1578 C57BL/6  
polypeptide Q6U7H8 UniProt | EBI | MGI Sequence Detail 395 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000012748 phosphatidylinositol 4-phosphate 5-kinase-like protein 1
  • EC
  • InterPro Domains
    IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
    IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
    IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
    IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory