About   Help   FAQ
Mgst2 Gene Detail
Summary
  • Symbol
    Mgst2
  • Name
    microsomal glutathione S-transferase 2
  • Synonyms
    GST2, MGC:41409, MGST-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448481
    NCBI Gene: 211666
Location & Maps
more
  • Sequence Map
    Chr3:51660360-51682677 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22318 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MGST2, microsomal glutathione S-transferase 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MGST2, microsomal glutathione S-transferase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GST2, MGST-II
  • Links
    NCBI Gene ID: 4258
    neXtProt AC: NX_Q99735

  • Chr Location
    4q28.3; chr4:139665768-139740745 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1811
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;2 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MGST2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    2
  • Radiation induced
    2
  • Genomic Mutations
    2 involving Mgst2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030621 VEGA Gene Model | MGI Sequence Detail 22318 C57BL/6J ±  kb
transcript OTTMUST00000075820 VEGA | MGI Sequence Detail 603 Not Applicable  
polypeptide OTTMUSP00000039816 VEGA | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    313 from dbSNP Build 137
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001446 5-lipoxygenase-activating protein
    IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain
    IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory