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Fchsd2 Gene Detail
Summary
  • Symbol
    Fchsd2
  • Name
    FCH and double SH3 domains 2
  • Synonyms
    mKIAA0769, Sh3md3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448475
    NCBI Gene: 207278
  • Alliance
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:100757836-100933613 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    720 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448475
protein coding gene Chr7:100742070-100933613 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032581
protein coding gene Chr7:104057394-104243309 (+)
A/J MGP_AJ_G0032555
protein coding gene Chr7:101402675-101582804 (+)
AKR/J MGP_AKRJ_G0032491
protein coding gene Chr7:103815503-104000759 (+)
BALB/cJ MGP_BALBcJ_G0032566
protein coding gene Chr7:101092054-101271868 (+)
C3H/HeJ MGP_C3HHeJ_G0032281
protein coding gene Chr7:104219644-104403706 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033064
protein coding gene Chr7:107995307-108177819 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030058
protein coding gene Chr7:103788730-103958477 (+)
CAST/EiJ MGP_CASTEiJ_G0031608
protein coding gene Chr7:95773011-95951987 (+)
CBA/J MGP_CBAJ_G0032248
protein coding gene Chr7:111719528-111918982 (+)
DBA/2J MGP_DBA2J_G0032399
protein coding gene Chr7:99757748-99936121 (+)
FVB/NJ MGP_FVBNJ_G0032356
protein coding gene Chr7:99517362-99705831 (+)
LP/J MGP_LPJ_G0032489
protein coding gene Chr7:105385141-105567523 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032389
protein coding gene Chr7:113071571-113285468 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033086
protein coding gene Chr7:103100609-103284015 (+)
PWK/PhJ MGP_PWKPhJ_G0031326
protein coding gene Chr7:92874271-93056648 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031169
protein coding gene Chr7:90397937-90582889 (+)
WSB/EiJ MGP_WSBEiJ_G0031725
protein coding gene Chr7:103801091-103994238 (+)



Homology
more
  • Human Ortholog
    FCHSD2, FCH and double SH3 domains 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FCHSD2, FCH and double SH3 domains 2
  • Synonyms
    NWK, NWK1, SH3MD3
  • Links
    NCBI Gene ID: 9873
    neXtProt AC: NX_O94868
    UniProt: O94868

  • Chr Location
    11q13.4; chr11:72836745-73142318 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 207278 NCBI Gene Model | MGI Sequence Detail 175778 C57BL/6J ±  kb
transcript NM_199012 RefSeq | MGI Sequence Detail 4376 C57BL/6  
polypeptide Q3USJ8 UniProt | EBI | MGI Sequence Detail 740 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 117
    cDNA 117

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142383
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory