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H4c2 Gene Detail
Summary
  • Symbol
    H4c2
  • Name
    H4 clustered histone 2
  • Synonyms
    Hist1h4b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448420
    NCBI Gene: 326620
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23940996-23941392 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448420
 protein coding gene Chr13:23940920-23941392 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020364
 protein coding gene Chr13:21200920-21201316 (+)
A/J MGP_AJ_G0020313
 protein coding gene Chr13:20809575-20810565 (+)
AKR/J MGP_AKRJ_G0020293
 protein coding gene Chr13:21063690-21064086 (+)
BALB/cJ MGP_BALBcJ_G0020311
 protein coding gene Chr13:20804118-20804514 (+)
C3H/HeJ MGP_C3HHeJ_G0020115
 protein coding gene Chr13:21135701-21136097 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020748
 protein coding gene Chr13:21981039-21981435 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018336
 protein coding gene Chr13:19584765-19585161 (+)
CAST/EiJ MGP_CASTEiJ_G0019634
 protein coding gene Chr13:20818574-20818970 (+)
CBA/J MGP_CBAJ_G0020069
 protein coding gene Chr13:22833058-22835649 (+)
DBA/2J MGP_DBA2J_G0020195
 protein coding gene Chr13:20338247-20338643 (+)
FVB/NJ MGP_FVBNJ_G0020179
 protein coding gene Chr13:19988821-19989217 (+)
LP/J MGP_LPJ_G0020268
 protein coding gene Chr13:21509115-21509511 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020206
 protein coding gene Chr13:23130923-23131319 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020790
 protein coding gene Chr13:20916496-20916892 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019203
 protein coding gene Chr13:19720622-19721042 (+)
WSB/EiJ MGP_WSBEiJ_G0019692
 protein coding gene Chr13:21053718-21054114 (+)



Homology
more
  • Human Ortholog
    H4C14, H4 clustered histone 14
  • Vertebrate Orthologs
    16
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H4C14, H4 clustered histone 14
  • Synonyms
    FO108, H4, H4-16, H4C1, H4C11, H4C12, H4C13, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4F2, H4FN, H4/n, HIST2H4, HIST2H4A
  • Links
    NCBI Gene ID: 8370
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    1q21.2; chr1:149832657-149839767 (+)  GRCh38
  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
  • Links
    NCBI Gene ID: 8367
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26204610-26205021 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H4c2
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    23
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069266 Ensembl Gene Model | MGI Sequence Detail 397 C57BL/6J ±  kb
transcript ENSMUST00000102965 Ensembl | MGI Sequence Detail 397 Not Applicable  
polypeptide ENSMUSP00000100030 Ensembl | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    Genomic 2
    cDNA 2
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:175731 Liu LJ, et al., Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene. 2011 Sep 1;483(1-2):1-10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory