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Hist2h2bb Gene Detail
Summary
  • Symbol
    Hist2h2bb
  • Name
    histone cluster 2, H2bb
  • Synonyms
    H2b-616
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448413
    NCBI Gene: 319189
  • Gene Overview
    MyGene.info: HIST2H2BF
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96269752-96270132 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.71 cM, cytoband F1-F2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448413
protein coding gene Chr3:96269700-96270192 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027615
protein coding gene Chr3:97082528-97082908 (+)
A/J MGP_AJ_G0027577
protein coding gene Chr3:94035288-94035668 (+)
AKR/J MGP_AKRJ_G0027544
protein coding gene Chr3:96242316-96242696 (+)
BALB/cJ MGP_BALBcJ_G0027587
protein coding gene Chr3:93823950-93824330 (+)
C3H/HeJ MGP_C3HHeJ_G0027319
protein coding gene Chr3:96523739-96524119 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028033
protein coding gene Chr3:100643432-100643812 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025375
protein coding gene Chr3:90355315-90355695 (+)
CAST/EiJ MGP_CASTEiJ_G0026772
protein coding gene Chr3:95838093-95838473 (+)
CBA/J MGP_CBAJ_G0027294
protein coding gene Chr3:104328288-104328668 (+)
DBA/2J MGP_DBA2J_G0027437
protein coding gene Chr3:93336614-93336994 (+)
FVB/NJ MGP_FVBNJ_G0027406
protein coding gene Chr3:91396694-91397074 (+)
LP/J MGP_LPJ_G0027542
protein coding gene Chr3:98407299-98407679 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027432
protein coding gene Chr3:110419035-110419415 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028087
protein coding gene Chr3:95872924-95873304 (+)
PWK/PhJ MGP_PWKPhJ_G0026499
protein coding gene Chr3:93235403-93235783 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026321
protein coding gene Chr3:94173968-94174348 (+)
WSB/EiJ MGP_WSBEiJ_G0026852
protein coding gene Chr3:96268296-96268676 (+)



Homology
more
  • Human Ortholog
    HIST2H2BF, histone cluster 2 H2B family member f
  • Vertebrate Orthologs
    7
  • Human Ortholog
    HIST2H2BF, histone cluster 2 H2B family member f
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 440689
    neXtProt AC: NX_Q5QNW6
    UniProt: Q5QNW6

  • Chr Location
    1q21.2; chr1:149782689-149812373 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000105827 Ensembl Gene Model | MGI Sequence Detail 381 C57BL/6J ±  kb
transcript ENSMUST00000177113 Ensembl | MGI Sequence Detail 381 Not Applicable  
polypeptide ENSMUSP00000135427 Ensembl | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Diseases 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:34961 Wang ZF, et al., Characterization of the 55-kb mouse histone gene cluster on chromosome 3. Genome Res. 1996 Aug;6(8):702-14
  • Latest
    J:197878 Santoro SW, et al., The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. Elife. 2012;1:e00070

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory