H2bc15 Gene Detail

Summary

• Symbol
  H2bc15
• Name
  H2B clustered histone 15
• Synonyms
  Hist1h2bn

• Feature Type
  protein coding gene
• IDs
  MGI:2448407
  NCBI Gene: 319187
• Member of
  Hist1 cluster
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr13:21938293-21938673 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, 7.95 cM, cytoband A2-A3
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  150 from dbSNP Build 142
• Strain Annotations
  8

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2448407	protein coding gene	Chr13:21938246-21938723 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020291	protein coding gene	Chr13:18989659-18990265 (-)
A/J	MGP_AJ_G0020253	protein coding gene	Chr13:18612780-18613112 (+)
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0020045	protein coding gene	Chr13:19020914-19021206 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0020125	protein coding gene	Chr13:18246011-18246513 (+)
FVB/NJ	MGP_FVBNJ_G0020104	protein coding gene	Chr13:17867599-17868085 (-)
LP/J	MGP_LPJ_G0020260	protein coding gene	Chr13:21428787-21438431 (+)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0020712	protein coding gene	Chr13:18743501-18743874 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  H2BC13, H2B clustered histone 13

• Vertebrate Orthologs
  11

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  H2BC13, H2B clustered histone 13
  
• Synonyms
  dJ97D16.4, H2B/c, H2BFC, HIST1H2BL
• Links
  HGNC:4748

  NCBI Gene ID: 8340

  UniProt: Q99880

  
  
• Chr Location
  6p22.1; chr6:27807479-27807929 (-)  GRCh38

---

• MGI Vertebrate Homology
  H2bc15 stringent orthology
  1 human;1 mouse;10 zebrafish
  
• HCOP
  vertebrate homology predictions: H2BC13
• Gene Tree
  H2bc15
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving H2bc15
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  9 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  16
• RefSeq
  2
• CCDS
  CCDS26294.1

• Ensembl
  ENSMUSG00000095217 (Evidence)
• NCBI Gene
  319187

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000095217	Ensembl Gene Model | MGI Sequence Detail	381	C57BL/6J
transcript	ENSMUST00000091709	Ensembl | MGI Sequence Detail	381	Not Applicable
polypeptide	ENSMUSP00000089301	Ensembl | MGI Sequence Detail	126	Not Applicable

Molecular
Reagents

• All nucleic 1

  Genomic 1

Other
Accession IDs

MGI:6324987

References

• Summaries
  All 17

  Phenotypes 8
• Earliest
  J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
• Latest
  J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44

TSS for H2bc15:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118790	Chr13:21938201-21938215 (+)	-85 bp
Tssr118791	Chr13:21938223-21938231 (+)	-66 bp
Tssr118792	Chr13:21938237-21938253 (+)	-48 bp
Tssr118793	Chr13:21938258-21938263 (+)	-32 bp