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H2bc12 Gene Detail
Summary
  • Symbol
    H2bc12
  • Name
    H2B clustered histone 12
  • Synonyms
    Hist1h2bk
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448399
    NCBI Gene: 319184
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:22220040-22220515 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 8.14 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448399
 protein coding gene Chr13:22219991-22220515 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020307
 protein coding gene Chr13:19356544-19356894 (+)
A/J MGP_AJ_G0020266
 protein coding gene Chr13:18910230-18910732 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020253
 protein coding gene Chr13:18960706-18961508 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0020692
 protein coding gene Chr13:20036396-20037646 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0020125
 protein coding gene Chr13:18203940-18204268 (+)
LP/J MGP_LPJ_G0020211
 protein coding gene Chr13:19585188-19585898 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020724
 protein coding gene Chr13:19040322-19040711 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    H2BC12, H2B clustered histone 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2BC12, H2B clustered histone 12
  • Synonyms
    H2BFAiii, H2BFT, H2BK, H2B/S, HIST1H2BK
  • Links
    NCBI Gene ID: 85236
    neXtProt AC: NX_O60814
    UniProt: O60814

  • Chr Location
    6p22.1; chr6:27138293-27146858 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062727 Ensembl Gene Model | MGI Sequence Detail 476 C57BL/6J ±  kb
transcript ENSMUST00000110455 Ensembl | MGI Sequence Detail 476 Not Applicable  
polypeptide ENSMUSP00000106085 Ensembl | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    Genomic 1
    cDNA 2
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory