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Hist1h2bb Gene Detail
Summary
  • Symbol
    Hist1h2bb
  • Name
    histone cluster 1, H2bb
  • Synonyms
    H2b-143
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448377
    NCBI Gene: 319178
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: HIST1H2BB
Location & Maps
more
  • Sequence Map
    Chr13:23746790-23747241 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      452 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.90 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HIST1H2BB, histone cluster 1 H2B family member b
  • Vertebrate Orthologs
    7
  • Human Ortholog
    HIST1H2BB, histone cluster 1 H2B family member b
    Orthology source: HomoloGene, HGNC
  • Synonyms
    H2B.1, H2B/f, H2BFF
  • Links
    NCBI Gene ID: 3018
    neXtProt AC: NX_P33778

  • Chr Location
    6p22.2; chr6:26043227-26043657 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    48
  • Chemically induced (other)
    1
  • Gene trapped
    46
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist1h2bb
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000581 VEGA Gene Model | MGI Sequence Detail 452 C57BL/6J ±  kb
transcript OTTMUST00000001171 VEGA | MGI Sequence Detail 452 Not Applicable  
polypeptide OTTMUSP00000000551 VEGA | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    57 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    Genomic 1
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:32514 Brown VD, et al., Structure of a cluster of mouse histone genes. Biochim Biophys Acta. 1996 Apr 10;1306(1):17-22
  • Latest
    J:149113 Das R, et al., Histone H2B as a functionally important plasminogen receptor on macrophages. Blood. 2007 Nov 15;110(10):3763-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory