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H3c13 Gene Detail
Summary
  • Symbol
    H3c13
  • Name
    H3 clustered histone 13
  • Synonyms
    H3-616, Hist2h3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448351
    NCBI Gene: 319154
  • Gene Overview
    MyGene.info: H3C2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96268654-96269141 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.71 cM, cytoband F1-F2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448351
protein coding gene Chr3:96268654-96269155 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027614
protein coding gene Chr3:97081430-97081917 (+)
A/J MGP_AJ_G0027574
protein coding gene Chr3:94034190-94034677 (+)
AKR/J MGP_AKRJ_G0027542
protein coding gene Chr3:96241218-96241705 (+)
BALB/cJ MGP_BALBcJ_G0027585
protein coding gene Chr3:93811196-93811683 (+)
C3H/HeJ MGP_C3HHeJ_G0027318
protein coding gene Chr3:96522626-96523128 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028032
protein coding gene Chr3:100640128-100642821 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025374
protein coding gene Chr3:90354207-90354694 (+)
CAST/EiJ MGP_CASTEiJ_G0026770
protein coding gene Chr3:95836094-95837482 (+)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027435
protein coding gene Chr3:93335015-93336003 (+)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028086
protein coding gene Chr3:95871860-95872313 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0026320
protein coding gene Chr3:94171746-94173356 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    H3C2, H3 clustered histone 2
  • Vertebrate Orthologs
    5
  • Human Ortholog
    H3C2, H3 clustered histone 2
    Orthology source: HomoloGene
  • Synonyms
    H3C1, H3C10, H3C11, H3C12, H3C3, H3C4, H3C6, H3C7, H3C8, H3FL, H3/l, HIST1H3B
  • Links
    NCBI Gene ID: 8358
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26031589-26032060 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c13
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074403 Ensembl Gene Model | MGI Sequence Detail 488 C57BL/6J ±  kb
transcript ENSMUST00000098843 Ensembl | MGI Sequence Detail 488 Not Applicable  
polypeptide ENSMUSP00000096442 Ensembl | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 7
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:34961 Wang ZF, et al., Characterization of the 55-kb mouse histone gene cluster on chromosome 3. Genome Res. 1996 Aug;6(8):702-14
  • Latest
    J:277247 Vetrivel S, et al., Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019 Apr 13;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory