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Hist1h3f Gene Detail
Summary
  • Symbol
    Hist1h3f
  • Name
    histone cluster 1, H3f
  • Synonyms
    H3.2-221
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448329
    NCBI Gene: 260423
  • Member of
    Hist1 cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23544052-23544954 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.78 cM, cytoband A2-A3
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    13
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448329
protein coding gene Chr13:23544052-23545312 (.)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020302
protein coding gene Chr13:20583274-20584333 (+)
AKR/J MGP_AKRJ_G0020276
protein coding gene Chr13:20835543-20835996 (+)
BALB/cJ MGP_BALBcJ_G0020292
protein coding gene Chr13:20572223-20573074 (+)
C3H/HeJ MGP_C3HHeJ_G0020099
protein coding gene Chr13:20908421-20909268 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020733
protein coding gene Chr13:21714379-21723273 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018321
protein coding gene Chr13:19402984-19403774 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020051
protein coding gene Chr13:22570093-22570838 (+)
DBA/2J MGP_DBA2J_G0020179
protein coding gene Chr13:20143316-20145338 (-)
FVB/NJ MGP_FVBNJ_G0020163
protein coding gene Chr13:19770279-19771390 (+)
LP/J MGP_LPJ_G0020251
protein coding gene Chr13:21304595-21306879 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020767
protein coding gene Chr13:20684941-20685691 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019189
protein coding gene Chr13:19497758-19498557 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    HIST2H3A, histone cluster 2 H3 family member a
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HIST2H3A, histone cluster 2 H3 family member a
    Orthology source: HomoloGene
  • Synonyms
    H3/n, H3/o
  • Links
    NCBI Gene ID: 333932
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149852619-149853125 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist1h3f
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 260423 NCBI Gene Model | MGI Sequence Detail 903 C57BL/6J ±  kb
transcript NM_013548 RefSeq | MGI Sequence Detail 903 C57BL/6  
polypeptide NP_038576 RefSeq | MGI Sequence Detail 136 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 19
    Genomic 11
    cDNA 6
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-10725, MGI:96093
References
more
  • Summaries
    All 55
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:249297 Pathania M, et al., H3.3(K27M) Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. Cancer Cell. 2017 Nov 13;32(5):684-700.e9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory