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H3c6 Gene Detail
Summary
  • Symbol
    H3c6
  • Name
    H3 clustered histone 6
  • Synonyms
    H3.1, H3-f, Hist1h3e
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448326
    NCBI Gene: 319151
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: H3C11
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23561534-23562369 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.79 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448326
protein coding gene Chr13:23561475-23562385 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020289
protein coding gene Chr13:20562755-20573074 (+)
C3H/HeJ MGP_C3HHeJ_G0020100
protein coding gene Chr13:20908423-20909268 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018320
protein coding gene Chr13:19402984-19403773 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020049
protein coding gene Chr13:22554206-22570838 (+)
DBA/2J MGP_DBA2J_G0020176
protein coding gene Chr13:20124935-20127118 (+)
FVB/NJ MGP_FVBNJ_G0020162
protein coding gene Chr13:19761311-19771390 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020764
protein coding gene Chr13:20673024-20685691 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019188
protein coding gene Chr13:19497758-19498556 (-)
WSB/EiJ MGP_WSBEiJ_G0019678
protein coding gene Chr13:20839867-20841418 (-)



Homology
more
  • Human Ortholog
    H3C11, H3 clustered histone 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    H3C11, H3 clustered histone 11
    Orthology source: HomoloGene
  • Synonyms
    H3C1, H3C10, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3/f, H3.f, H3FF, HIST1H3I
  • Links
    NCBI Gene ID: 8354
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.1; chr6:27871845-27872321 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c6
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069273 Ensembl Gene Model | MGI Sequence Detail 836 C57BL/6J ±  kb
transcript ENSMUST00000105107 Ensembl | MGI Sequence Detail 836 Not Applicable  
polypeptide ENSMUSP00000100739 Ensembl | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:256374 Ogoh H, et al., Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development. Sci Rep. 2017 Sep 20;7(1):11922

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory