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H3c2 Gene Detail
Summary
  • Symbol
    H3c2
  • Name
    H3 clustered histone 2
  • Synonyms
    H3-53, Hist1h3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448319
    NCBI Gene: 319150
  • Member of
    Hist1 cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23936328-23936823 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448319
protein coding gene Chr13:23936250-23936869 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020363
protein coding gene Chr13:21196238-21196800 (+)
A/J MGP_AJ_G0020312
protein coding gene Chr13:20804836-20805455 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020310
protein coding gene Chr13:20794253-20799998 (+)
C3H/HeJ MGP_C3HHeJ_G0020114
protein coding gene Chr13:21130962-21131581 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018335
protein coding gene Chr13:19579983-19580521 (+)
CAST/EiJ MGP_CASTEiJ_G0019633
protein coding gene Chr13:20812158-20814398 (+)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0020194
protein coding gene Chr13:20333570-20334127 (+)
FVB/NJ MGP_FVBNJ_G0020178
protein coding gene Chr13:19984082-19984701 (+)
LP/J MGP_LPJ_G0020267
protein coding gene Chr13:21503937-21504939 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020205
protein coding gene Chr13:23114822-23123078 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020789
protein coding gene Chr13:20910869-20912376 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019202
protein coding gene Chr13:19717873-19794572 (+)
WSB/EiJ MGP_WSBEiJ_G0019691
protein coding gene Chr13:21048972-21049591 (+)



Homology
less
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319150 NCBI Gene Model | MGI Sequence Detail 496 C57BL/6J ±  kb
transcript NM_178203 RefSeq | MGI Sequence Detail 496 C57BL/6  
polypeptide P84228 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:285841 Fortin J, et al., Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas. Cancer Cell. 2020 Mar 16;37(3):308-323.e12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory