About   Help   FAQ
Hist2h2ac Gene Detail
Summary
  • Symbol
    Hist2h2ac
  • Name
    histone cluster 2, H2ac
  • Synonyms
    H2a-613b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448316
    NCBI Gene: 319176
  • Gene Overview
    MyGene.info: HIST2H2AC
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96220413-96220880 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.67 cM, cytoband F1-F2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448316
protein coding gene Chr3:96220361-96220880 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027610
protein coding gene Chr3:97027160-97027679 (-)
A/J MGP_AJ_G0027569
protein coding gene Chr3:93981273-93981792 (-)
AKR/J MGP_AKRJ_G0027536
protein coding gene Chr3:96186969-96187494 (-)
BALB/cJ MGP_BALBcJ_G0027581
protein coding gene Chr3:93761751-93762270 (-)
C3H/HeJ MGP_C3HHeJ_G0027314
protein coding gene Chr3:96470588-96471107 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028029
protein coding gene Chr3:100587320-100589108 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025369
protein coding gene Chr3:90306759-90307277 (-)
CAST/EiJ MGP_CASTEiJ_G0026764
protein coding gene Chr3:95759602-95762948 (-)
CBA/J MGP_CBAJ_G0027290
protein coding gene Chr3:104266163-104270257 (-)
DBA/2J MGP_DBA2J_G0027430
protein coding gene Chr3:93285984-93286503 (-)
FVB/NJ MGP_FVBNJ_G0027401
protein coding gene Chr3:91348464-91348941 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0027428
protein coding gene Chr3:110369101-110369620 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028083
protein coding gene Chr3:95817438-95819303 (-)
PWK/PhJ MGP_PWKPhJ_G0026492
protein coding gene Chr3:93172121-93172712 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026313
protein coding gene Chr3:94121267-94121786 (-)
WSB/EiJ MGP_WSBEiJ_G0026846
protein coding gene Chr3:96215547-96216066 (-)



Homology
more
  • Human Ortholog
    HIST2H2AC, histone cluster 2 H2A family member c
  • Vertebrate Orthologs
    16
  • Human Ortholog
    HIST2H2AC, histone cluster 2 H2A family member c
    Orthology source: HomoloGene
  • Synonyms
    H2A, H2AFQ, H2A-GL101, H2A/q
  • Links
    NCBI Gene ID: 8338
    neXtProt AC: NX_Q16777
    UniProt: Q16777

  • Chr Location
    1q21.2; chr1:149886975-149887411 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist2h2ac
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319176 NCBI Gene Model | MGI Sequence Detail 468 C57BL/6J ±  kb
transcript NM_175662 RefSeq | MGI Sequence Detail 468 C57BL/6  
polypeptide Q64523 UniProt | EBI | MGI Sequence Detail 129 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Diseases 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:34961 Wang ZF, et al., Characterization of the 55-kb mouse histone gene cluster on chromosome 3. Genome Res. 1996 Aug;6(8):702-14
  • Latest
    J:194424 Yasunaga S, et al., Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4. Mol Cell Biol. 2013 Feb;33(4):644-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory