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Hist1h2ac Gene Detail
Summary
  • Symbol
    Hist1h2ac
  • Name
    histone cluster 1, H2ac
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448287
    NCBI Gene: 319164
  • Member of
    Hist1 cluster
  • Gene Overview
    MyGene.info: HIST1H2AK
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23683473-23683959 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.87 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448287
protein coding gene Chr13:23681467-23683959 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020307
protein coding gene Chr13:20730546-20731021 (-)
AKR/J MGP_AKRJ_G0020286
protein coding gene Chr13:20983941-20984416 (-)
BALB/cJ MGP_BALBcJ_G0020303
protein coding gene Chr13:20723096-20723571 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0020741
protein coding gene Chr13:21896573-21897324 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020059
protein coding gene Chr13:22740369-22748871 (-)
DBA/2J MGP_DBA2J_G0020186
protein coding gene Chr13:20262261-20262758 (-)
FVB/NJ MGP_FVBNJ_G0020171
protein coding gene Chr13:19914585-19915060 (-)
LP/J MGP_LPJ_G0020253
protein coding gene Chr13:21315049-21315364 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020780
protein coding gene Chr13:20832992-20833467 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    HIST1H2AK, histone cluster 1 H2A family member k
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HIST1H2AK, histone cluster 1 H2A family member k
    Orthology source: HomoloGene
  • Synonyms
    H2A/d, H2AFD
  • Links
    NCBI Gene ID: 8330
    neXtProt AC: NX_P0C0S8
    UniProt: P0C0S8, Q99878

  • Chr Location
    6p22.1; chr6:27837880-27838339 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist1h2ac
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319164 NCBI Gene Model | MGI Sequence Detail 487 C57BL/6J ±  kb
transcript NM_178189 RefSeq | MGI Sequence Detail 487 C57BL/6  
polypeptide NP_835496 RefSeq | MGI Sequence Detail 130 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory