H2ac19 Gene Detail

Summary

• Symbol
  H2ac19
• Name
  H2A clustered histone 19
• Synonyms
  H2a-614, Hist2h2aa2

• Feature Type
  protein coding gene
• IDs
  MGI:2448283
  NCBI Gene: 319192
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr3:96147065-96147592 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 41.69 cM, cytoband F1-F2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  105 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2448283	protein coding gene	Chr3:96147065-96147638 (-)
129S1/SvImJ	ENSMUSG00200040034	protein coding gene	Chr3:92815133-92815718 (-)
A/J	ENSMUSG00195041059	protein coding gene	Chr3:93143444-93144029 (-)
A/J	ENSMUSG00195041077	protein coding gene	Chr3:93149196-93149781 (+)
AKR/J	ENSMUSG00220033224	protein coding gene	Chr3:91526297-91526824 (-)
AKR/J	ENSMUSG00220033246	protein coding gene	Chr3:91532045-91532630 (+)
BALB/cJ	ENSMUSG00180036095	protein coding gene	Chr3:93140834-93141419 (+)
BALB/cJ	ENSMUSG00180036053	protein coding gene	Chr3:93135085-93135670 (-)
C3H/HeJ	ENSMUSG00175029096	protein coding gene	Chr3:92773066-92773651 (-)
C3H/HeJ	ENSMUSG00175029115	protein coding gene	Chr3:92778818-92779403 (+)
C57BL/6NJ	ENSMUSG00215013558	protein coding gene	Chr3:93507969-93508554 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210051086	protein coding gene	Chr3:93324796-93325381 (-)
CBA/J	ENSMUSG00210051090	protein coding gene	Chr3:93330548-93331133 (+)
DBA/2J	ENSMUSG00185037170	protein coding gene	Chr3:93749004-93749589 (+)
FVB/NJ	ENSMUSG00205047944	protein coding gene	Chr3:92431434-92432019 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230043924	protein coding gene	Chr3:95684258-95684843 (+)
NOD/ShiLtJ	ENSMUSG00190035976	protein coding gene	Chr3:93850421-93851006 (+)
NOD/ShiLtJ	ENSMUSG00190035937	protein coding gene	Chr3:93844636-93845221 (-)
NZO/HlLtJ	ENSMUSG00225009252	protein coding gene	Chr3:98102969-98103554 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  H2AC18, H2A clustered histone 18

• Vertebrate Orthologs
  29

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  H2AC18, H2A clustered histone 18
  
• Synonyms
  H2A, H2A.2, H2a-615, H2AFO, H2A/O, H2A/q, HIST2H2AA, HIST2H2AA3
• Links
  HGNC:4736

  NCBI Gene ID: 8337

  UniProt: Q6FI13

  
  
• Chr Location
  1q21.2; chr1:149842218-149842750 (-)  GRCh38

---

• Human Ortholog
  H2AC19, H2A clustered histone 19
  
• Synonyms
  H2A/R, HIST2H2AA4
• Links
  HGNC:29668

  NCBI Gene ID: 723790

  UniProt: Q6FI13

  
  
• Chr Location
  1q21.2; chr1:149851061-149851652 (+)  GRCh38

---

• MGI Vertebrate Homology
  H2ac19 stringent orthology
  2 human;1 mouse;2 rat;25 zebrafish
  
• HCOP
  vertebrate homology predictions: H2AC18, H2AC19
• Gene Tree
  H2ac19
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving H2ac19
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  964
• Tissues
  20
• cDNA Data
  7
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  37
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS57241.1

• Ensembl
  ENSMUSG00000063954 (Evidence)
• NCBI Gene
  319192

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000063954	Ensembl Gene Model | MGI Sequence Detail	528	C57BL/6J
transcript	ENSMUST00000074976	Ensembl | MGI Sequence Detail	528	Not Applicable
polypeptide	ENSMUSP00000100581	Ensembl | MGI Sequence Detail	130	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 9

  cDNA 8

  Primer pair 1

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:6325015

References

• Summaries
  All 24

  Developmental Gene Expression 2

  Diseases 1

  Phenotypes 4
• Earliest
  J:19916 Moss SB, et al., An alternative pathway of histone mRNA 3' end formation in mouse round spermatids. Nucleic Acids Res. 1994 Aug 11;22(15):3160-6
• Latest
  J:338193 Slabber CF, et al., The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration. Sci Signal. 2023 May 30;16(787):eade8029

TSS for H2ac19:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34599	Chr3:96147633-96147654 (-)	-52 bp