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Cldnd1 Gene Detail
Summary
  • Symbol
    Cldnd1
  • Name
    claudin domain containing 1
  • Synonyms
    1110019C08Rik, Cldn25
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447860
    NCBI Gene: 224250
  • Gene Overview
    MyGene.info: CLDND1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:58727910-58734247 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 34.83 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447860
protein coding gene Chr16:58727910-58734251 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022907
protein coding gene Chr16:57909061-57915403 (+)
A/J MGP_AJ_G0022874
protein coding gene Chr16:55441806-55450961 (+)
AKR/J MGP_AKRJ_G0022846
protein coding gene Chr16:57163441-57169783 (+)
BALB/cJ MGP_BALBcJ_G0022874
protein coding gene Chr16:55527665-55534007 (+)
C3H/HeJ MGP_C3HHeJ_G0022637
protein coding gene Chr16:57394703-57401045 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023322
protein coding gene Chr16:59523859-59530200 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020833
protein coding gene Chr16:54976533-54982941 (+)
CAST/EiJ MGP_CASTEiJ_G0022164
protein coding gene Chr16:57730382-57736696 (+)
CBA/J MGP_CBAJ_G0022610
protein coding gene Chr16:61908496-61914808 (+)
DBA/2J MGP_DBA2J_G0022742
protein coding gene Chr16:55161000-55167342 (+)
FVB/NJ MGP_FVBNJ_G0022717
protein coding gene Chr16:54920366-54926708 (+)
LP/J MGP_LPJ_G0022809
protein coding gene Chr16:57707464-57713806 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022735
protein coding gene Chr16:62280417-62286759 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023337
protein coding gene Chr16:57302386-57308727 (+)
PWK/PhJ MGP_PWKPhJ_G0021903
protein coding gene Chr16:55466764-55473077 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021733
protein coding gene Chr16:57063292-57069637 (+)
WSB/EiJ MGP_WSBEiJ_G0022208
protein coding gene Chr16:57342688-57349029 (+)



Homology
more
  • Human Ortholog
    CLDND1, claudin domain containing 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CLDND1, claudin domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C3orf4, GENX-3745, Z38
  • Links
    NCBI Gene ID: 56650
    neXtProt AC: NX_Q9NY35
    UniProt: Q9NY35

  • Chr Location
    3q11.2; chr3:98515473-98523066 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10534
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CLDND1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 224250 NCBI Gene Model | MGI Sequence Detail 6338 C57BL/6J ±  kb
transcript NM_001356488 RefSeq | MGI Sequence Detail 2209 C57BL/6  
polypeptide Q9CQX5 UniProt | EBI | MGI Sequence Detail 253 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146328, MGI:2146504, MGI:2146640
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory