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Sfmbt2 Gene Detail
Summary
  • Symbol
    Sfmbt2
  • Name
    Scm-like with four mbt domains 2
  • Synonyms
    D2Wsu23e, D330030P06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447794
    NCBI Gene: 353282
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:10370510-10595253 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 7.81 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    958 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447794
protein coding gene Chr2:10370440-10595253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025341
protein coding gene Chr2:7724655-7950607 (+)
A/J MGP_AJ_G0025318
protein coding gene Chr2:7389659-7617655 (+)
AKR/J MGP_AKRJ_G0025287
protein coding gene Chr2:7632652-7869619 (+)
BALB/cJ MGP_BALBcJ_G0025314
protein coding gene Chr2:7393246-7599291 (+)
C3H/HeJ MGP_C3HHeJ_G0025074
protein coding gene Chr2:7592564-7802347 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025756
protein coding gene Chr2:7930072-8155302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023170
protein coding gene Chr2:6903276-7115286 (+)
CAST/EiJ MGP_CASTEiJ_G0024537
protein coding gene Chr2:7617030-7830923 (+)
CBA/J MGP_CBAJ_G0025053
protein coding gene Chr2:8263898-8500082 (+)
DBA/2J MGP_DBA2J_G0025185
protein coding gene Chr2:7322572-7544948 (+)
FVB/NJ MGP_FVBNJ_G0025147
protein coding gene Chr2:7269362-7489597 (+)
LP/J MGP_LPJ_G0025271
protein coding gene Chr2:7613213-7868197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025179
protein coding gene Chr2:8206016-8449887 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025814
protein coding gene Chr2:7583014-7810426 (+)
PWK/PhJ MGP_PWKPhJ_G0024288
protein coding gene Chr2:7314649-7518258 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024088
protein coding gene Chr2:7584965-7791812 (+)
WSB/EiJ MGP_WSBEiJ_G0024607
protein coding gene Chr2:7672921-7908818 (+)



Homology
more
  • Human Ortholog
    SFMBT2, Scm like with four mbt domains 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SFMBT2, Scm like with four mbt domains 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 57713
    neXtProt AC: NX_Q5VUG0
    UniProt: Q5VUG0

  • Chr Location
    10p14; chr10:7158624-7411486 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 82485
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SFMBT2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061186 Ensembl Gene Model | MGI Sequence Detail 224744 C57BL/6J ±  kb
transcript ENSMUST00000041105 Ensembl | MGI Sequence Detail 7874 Not Applicable  
polypeptide ENSMUSP00000040575 Ensembl | MGI Sequence Detail 975 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 65
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-34243, MGI:106549, MGI:2444880
References
more
  • Summaries
    All 41
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:254511 Inoue K, et al., The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory