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Nat8l
Gene Detail
Symbol

Name
ID
Nat8l
N-acetyltransferase 8-like
MGI:2447776
Synonyms
1110038O08Rik, Shati
Feature Type
protein coding gene
Genetic Map
Chromosome 5
17.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:33995984-34005916 bp, + strand
From NCBI annotation of GRCm38

  9933 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19546  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NAT8L
Gene Tree: Nat8l

Human
homologs
NAT8L, N-acetyltransferase 8-like (GCN5-related, putative)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 339983
neXtProt AC: NX_Q8N9F0

Human Synonyms: CML3, NACED, NAT8-LIKE

Human Chr (Location): 4p16.3; chr4:2059512-2069089 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NAT8L

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Chemically induced (ENU)(1) Radiation induced(6) Targeted(4)
Genomic Mutations involving Nat8l (7)
Incidental mutations (data from APF )
 
Mice homozygous for a null mutation display abnormal responses to novelty and decreased social investigation in a novel environment.
 
Mutations Annotated to Human Diseases (4)    Phenotype Images(4)
Interactions
Nat8l interacts with 380 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (11)    Tissues (9)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 11
cDNA source data(29)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nat8l ; ZFIN nat8l    NEW 
Molecular
reagents
All nucleic(30) cDNA(30)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000048142 (Evidence)
Entrez Gene 269642 (Evidence)
UniGene 274610
DFCI TC1577499, TC1600855, TC1651491
DoTS DT.60105126, DT.488120
NIA Mouse Gene Index U042630
EC 2.3.1.17
Consensus CDS Project CCDS19210.1
International Mouse Phenotyping Consortium Status Nat8l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 269642 NCBI Gene Model | MGI Sequence Detail 9933 C57BL/6J ±  kb
transcript NM_001001985 RefSeq | MGI Sequence Detail 6529 C57BL/6 
polypeptide Q3UGX3 UniProt | EBI | MGI Sequence Detail 299 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016181 Acyl-CoA N-acyltransferase
InterPro IPR000182 GNAT domain
Protein Ontology PR:000011004 N-acetylaspartate synthetase
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:217675 Gao Z, et al., An AUTS2-Polycomb complex activates gene expression in the CNS. Nature. 2014 Dec 18;516(7531):349-54
All references(40)
Other
accession IDs
MGI:1916012

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory