Klk14
Gene Detail

Symbol Name ID

Klk14 kallikrein related-peptidase 14 MGI:2447564

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:43690418-43695536 bp, + strand From VEGA annotation of GRCm38   5119 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69348  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Klk14

Human homologs

Human Homolog		KLK14, kallikrein-related peptidase 14
NCBI Gene ID		43847
neXtProt AC		NX_Q9P0G3
Human Synonyms		KLK-L6
Human Chr (Location)		19q13.3-q13.4; chr19:51581154-51587502 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	epidermis morphogenesis, fertilization, ...
Component	extracellular region, extracellular space
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(4)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000027218 (Evidence)
Ensembl Gene Model	ENSMUSG00000044737 (Evidence)
Entrez Gene	317653 (Evidence)
UniGene	247377
DFCI	TC1602888
DoTS	DT.94254556
NIA Mouse Gene Index	U056144
EC	3.4.21.-
Consensus CDS Project	CCDS21180.1
International Mouse Knockout Project Status	Klk14

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027218	VEGA Gene Model | MGI Sequence Detail	5119	C57BL/6J
transcript	OTTMUST00000067311	VEGA | MGI Sequence Detail	1271	Not Applicable
polypeptide	OTTMUSP00000033840	VEGA | MGI Sequence Detail	250	Not Applicable

All sequences(18) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(32 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000009411	kallikrein-14

References

(Earliest) J:80434 Hernandez A, et al., The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. Endocrinology. 2002 Nov;143(11):4483-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)