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Klk14
Gene Detail
Symbol

Name
ID
Klk14
kallikrein related-peptidase 14
MGI:2447564
Feature Type
protein coding gene
Genetic Map
Chromosome 7
28.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:43690418-43695536 bp, + strand
From VEGA annotation of GRCm38

  5119 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69348  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog

HCOP human homology predictions: KLK14
Protein SuperFamily: trypsin
Gene Tree: Klk14

Human
homologs
KLK14, kallikrein-related peptidase 14
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 43847
neXtProt AC: NX_Q9P0G3

Human Synonyms: KLK-L6

Human Chr (Location): 19q13.3-q13.4; chr19:51077879-51086458 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klk14 interacts with 63 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process epidermis morphogenesis, fertilization, ...
Component extracellular exosome, extracellular region, ...
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000027218 (Evidence)
Ensembl Gene Model ENSMUSG00000044737 (Evidence)
Entrez Gene 317653 (Evidence)
UniGene 247377
DFCI TC1602888
DoTS DT.94254556
NIA Mouse Gene Index U056144
EC 3.4.21.-
Consensus CDS Project CCDS21180.1
International Mouse Phenotyping Consortium Status Klk14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027218 VEGA Gene Model | MGI Sequence Detail 5119 C57BL/6J ±  kb
transcript OTTMUST00000067311 VEGA | MGI Sequence Detail 1271 Not Applicable 
polypeptide OTTMUSP00000033840 VEGA | MGI Sequence Detail 250 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(72 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000009411 kallikrein-14
References
(Earliest) J:80434 Hernandez A, et al., The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. Endocrinology. 2002 Nov;143(11):4483-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory