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Klk15 Gene Detail
Summary
  • Symbol
    Klk15
  • Name
    kallikrein related-peptidase 15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447533
    NCBI Gene: 317652
Location & Maps
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  • Sequence Map
    Chr7:43933771-43939590 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5820 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    KLK15, kallikrein related peptidase 15
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KLK15, kallikrein related peptidase 15
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ACO, HSRNASPH
  • Links
    NCBI Gene ID: 55554
    neXtProt AC: NX_Q9H2R5

  • Chr Location
    19q13.41; chr19:50825289-50836035 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027231 VEGA Gene Model | MGI Sequence Detail 5820 C57BL/6J ±  kb
transcript OTTMUST00000067343 VEGA | MGI Sequence Detail 765 Not Applicable  
polypeptide OTTMUSP00000033867 VEGA | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    144 from dbSNP Build 137
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin-type
    IPR009003 Peptidase S1, PA clan
    IPR018114 Peptidase S1, trypsin family, active site
    IPR001254 Serine proteases, trypsin domain
Molecular
Reagents
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  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80454 Olsson AY, et al., Organization and evolution of the glandular kallikrein locus in Mus musculus. Biochem Biophys Res Commun. 2002 Nov 29;299(2):305-11
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory