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Klk15 Gene Detail
Summary
  • Symbol
    Klk15
  • Name
    kallikrein related-peptidase 15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447533
    NCBI Gene: 317652
  • Gene Overview
    MyGene.info: KLK15
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:43933740-43939639 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    259 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447533
protein coding gene Chr7:43929405-43939852 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032148
protein coding gene Chr7:43986095-43991956 (+)
A/J MGP_AJ_G0032133
protein coding gene Chr7:43065628-43071368 (+)
AKR/J MGP_AKRJ_G0032063
protein coding gene Chr7:44459818-44465708 (+)
BALB/cJ MGP_BALBcJ_G0032138
protein coding gene Chr7:43186332-43192513 (+)
C3H/HeJ MGP_C3HHeJ_G0031854
protein coding gene Chr7:44959910-44966594 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032622
protein coding gene Chr7:46212246-46219016 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029645
protein coding gene Chr7:45194650-45837093 (+)
CAST/EiJ MGP_CASTEiJ_G0031184
protein coding gene Chr7:36156664-36165670 (+)
CBA/J MGP_CBAJ_G0031823
protein coding gene Chr7:47671244-47677628 (+)
DBA/2J MGP_DBA2J_G0031972
protein coding gene Chr7:42872381-42878649 (+)
FVB/NJ MGP_FVBNJ_G0031933
protein coding gene Chr7:42583501-42589400 (+)
LP/J MGP_LPJ_G0032051
protein coding gene Chr7:44727673-44734959 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031969
protein coding gene Chr7:46591332-46597217 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032642
protein coding gene Chr7:43581478-43587390 (+)
PWK/PhJ MGP_PWKPhJ_G0030905
protein coding gene Chr7:36332864-36338813 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030744
protein coding gene Chr7:31619973-31625918 (+)
WSB/EiJ MGP_WSBEiJ_G0031298
protein coding gene Chr7:44141053-44146951 (+)



Homology
more
  • Human Ortholog
    KLK15, kallikrein related peptidase 15
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KLK15, kallikrein related peptidase 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACO, HSRNASPH
  • Links
    NCBI Gene ID: 55554
    neXtProt AC: NX_Q9H2R5
    UniProt: Q9H2R5

  • Chr Location
    19q13.33; chr19:50825289-50834337 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055193 Ensembl Gene Model | MGI Sequence Detail 5900 C57BL/6J ±  kb
transcript ENSMUST00000068625 Ensembl | MGI Sequence Detail 845 Not Applicable  
polypeptide ENSMUSP00000066969 Ensembl | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80454 Olsson AY, et al., Organization and evolution of the glandular kallikrein locus in Mus musculus. Biochem Biophys Res Commun. 2002 Nov 29;299(2):305-11
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory