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Vgll2 Gene Detail
Summary
  • Symbol
    Vgll2
  • Name
    vestigial like family member 2
  • Synonyms
    C130057C21Rik, Vgl-2, Vito1, VITO-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447460
    NCBI Gene: 215031
Location & Maps
more
  • Sequence Map
    Chr10:52022502-52028471 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5970 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 26.16 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    VGLL2, vestigial like family member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VGLL2, vestigial like family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    VGL2, VITO1
  • Links
    NCBI Gene ID: 245806
    neXtProt AC: NX_Q8N8G2

  • Chr Location
    6q22.1; chr6:117265558-117273565 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 35066
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VGLL2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Vgll2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027947 VEGA Gene Model | MGI Sequence Detail 5970 C57BL/6J ±  kb
transcript OTTMUST00000069228 VEGA | MGI Sequence Detail 1650 Not Applicable  
polypeptide OTTMUSP00000035128 VEGA | MGI Sequence Detail 322 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2443345
References
more
  • Summaries
    All 25
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:222450 Uribe V, et al., Arid3b is essential for second heart field cell deployment and heart patterning. Development. 2014 Nov;141(21):4168-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory