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Cmtm7 Gene Detail
Summary
  • Symbol
    Cmtm7
  • Name
    CKLF-like MARVEL transmembrane domain containing 7
  • Synonyms
    Cklfsf7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447166
    NCBI Gene: 102545
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:114756836-114781856 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 65.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    332 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447166
protein coding gene Chr9:114756836-114781993 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035394
protein coding gene Chr9:117218589-117243569 (-)
A/J MGP_AJ_G0035374
protein coding gene Chr9:112923665-112948785 (-)
AKR/J MGP_AKRJ_G0035307
protein coding gene Chr9:115797845-115823420 (-)
BALB/cJ MGP_BALBcJ_G0035370
protein coding gene Chr9:112729749-112754884 (-)
C3H/HeJ MGP_C3HHeJ_G0035078
protein coding gene Chr9:116296958-116322061 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035893
protein coding gene Chr9:120426857-120461623 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032776
protein coding gene Chr9:110220405-110245644 (-)
CAST/EiJ MGP_CASTEiJ_G0034383
protein coding gene Chr9:116163748-116188564 (-)
CBA/J MGP_CBAJ_G0035045
protein coding gene Chr9:124945508-124970623 (-)
DBA/2J MGP_DBA2J_G0035204
protein coding gene Chr9:112394767-112420703 (-)
FVB/NJ MGP_FVBNJ_G0035151
protein coding gene Chr9:111220185-111248187 (-)
LP/J MGP_LPJ_G0035283
protein coding gene Chr9:117557081-117582216 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035192
protein coding gene Chr9:126161046-126188900 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035912
protein coding gene Chr9:116172445-116197800 (-)
PWK/PhJ MGP_PWKPhJ_G0034089
protein coding gene Chr9:112703736-112730466 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033923
protein coding gene Chr9:116216273-116241353 (-)
WSB/EiJ MGP_WSBEiJ_G0034503
protein coding gene Chr9:116054980-116081288 (-)



Homology
more
  • Human Ortholog
    CMTM7, CKLF like MARVEL transmembrane domain containing 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CMTM7, CKLF like MARVEL transmembrane domain containing 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CKLFSF7
  • Links
    NCBI Gene ID: 112616
    neXtProt AC: NX_Q96FZ5
    UniProt: Q96FZ5

  • Chr Location
    3p22.3; chr3:32391671-32455528 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 15882
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CMTM7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Heterozygous mice die shortly after birth. Null mutations in this gene are haploinsufficient. A chimeric mouse showed defects in B-1a cell numbers and physiology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032436 Ensembl Gene Model | MGI Sequence Detail 25021 C57BL/6J ±  kb
transcript ENSMUST00000035009 Ensembl | MGI Sequence Detail 993 Not Applicable  
polypeptide ENSMUSP00000035009 Ensembl | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143082
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:84235 Han W, et al., Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Genomics. 2003 Jun;81(6):609-17
  • Latest
    J:207033 Zhang Y, et al., A role for CMTM7 in BCR expression and survival in B-1a but not B-2 cells. Int Immunol. 2014 Jan;26(1):47-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory