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St18 Gene Detail
Summary
  • Symbol
    St18
  • Name
    suppression of tumorigenicity 18
  • Synonyms
    mKIAA0535, Myt3, Nzf3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446700
    NCBI Gene: 240690
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:6487231-6860940 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 1.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2223 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446700
protein coding gene Chr1:6487231-6860940 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015820
protein coding gene Chr1:3691040-4089826 (+)
A/J MGP_AJ_G0015802
protein coding gene Chr1:3637866-4023510 (+)
AKR/J MGP_AKRJ_G0015761
protein coding gene Chr1:3639265-4011548 (+)
BALB/cJ MGP_BALBcJ_G0015758
protein coding gene Chr1:3516876-3903971 (+)
C3H/HeJ MGP_C3HHeJ_G0015592
protein coding gene Chr1:3600147-3972343 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016210
protein coding gene Chr1:3763176-4201077 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013932
protein coding gene Chr1:3118577-3457293 (+)
CAST/EiJ MGP_CASTEiJ_G0015172
protein coding gene Chr1:3770620-4160810 (+)
CBA/J MGP_CBAJ_G0015565
protein coding gene Chr1:3940494-4348487 (+)
DBA/2J MGP_DBA2J_G0015664
protein coding gene Chr1:3468254-3843115 (+)
FVB/NJ MGP_FVBNJ_G0015669
protein coding gene Chr1:3425317-3784257 (+)
LP/J MGP_LPJ_G0015737
protein coding gene Chr1:3773494-4158208 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015688
protein coding gene Chr1:4209844-4615251 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016257
protein coding gene Chr1:3584524-3960000 (+)
PWK/PhJ MGP_PWKPhJ_G0014956
protein coding gene Chr1:3363524-3727951 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014736
protein coding gene Chr1:3760783-4143249 (+)
WSB/EiJ MGP_WSBEiJ_G0015236
protein coding gene Chr1:3536298-3898254 (+)



Homology
more
  • Human Ortholog
    ST18, ST18 C2H2C-type zinc finger transcription factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ST18, ST18 C2H2C-type zinc finger transcription factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NZF3, NZF-3, ZC2H2C3, ZC2HC10, ZNF387
  • Links
    NCBI Gene ID: 9705
    neXtProt AC: NX_O60284
    UniProt: O60284

  • Chr Location
    8q11.23; chr8:52110832-52409879 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8792
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ST18
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 240690 NCBI Gene Model | MGI Sequence Detail 373710 C57BL/6J ±  kb
    transcript NM_001244692 RefSeq | MGI Sequence Detail 5913 C57BL/6  
    polypeptide Q80TY4 UniProt | EBI | MGI Sequence Detail 1045 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      cDNA 24
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2138535
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
    • Latest
      J:266826 Sandberg M, et al., Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. Neuron. 2016 Sep 21;91(6):1260-1275

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
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    last database update
    05/07/2019
    MGI 6.14
    The Jackson Laboratory