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Map3k7cl Gene Detail
Summary
  • Symbol
    Map3k7cl
  • Name
    Map3k7 C-terminal like
  • Synonyms
    ORF63
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446584
    NCBI Gene: 224419
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:87350218-87392224 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 49.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1703 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446584
 protein coding gene Chr16:87350208-87392224 (+)
129S1/SvImJ ENSMUSG00200036733
 protein coding gene Chr16:84211257-84259952 (+)
A/J ENSMUSG00195025893
 protein coding gene Chr16:84020232-84068858 (+)
AKR/J ENSMUSG00220015472
 protein coding gene Chr16:84217661-84260176 (+)
BALB/cJ ENSMUSG00180014453
 protein coding gene Chr16:84098315-84140807 (+)
C3H/HeJ ENSMUSG00175014364
 protein coding gene Chr16:84427884-84476504 (+)
C57BL/6NJ ENSMUSG00215022005
 protein coding gene Chr16:84230561-84272576 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020901
 protein coding gene Chr16:82059141-82097324 (+)
CAST/EiJ ENSTCUG00005019507
 protein coding gene Chr16:83790351-83832308 (+)
CBA/J ENSMUSG00210037347
 protein coding gene Chr16:84324157-84366643 (+)
DBA/2J ENSMUSG00185032448
 protein coding gene Chr16:84277171-84319178 (+)
FVB/NJ ENSMUSG00205015540
 protein coding gene Chr16:84071390-84120023 (+)
JF1/MsJ ENSUMUG00000028009
 protein coding gene Chr16:84400693-84443494 (+)
LP/J ENSMUSG00230030844
 protein coding gene Chr16:86772316-86821018 (+)
NOD/ShiLtJ ENSMUSG00190023602
 protein coding gene Chr16:84237056-84285672 (+)
NZO/HlLtJ ENSMUSG00225030731
 protein coding gene Chr16:89954664-90008434 (+)
PWK/PhJ ENSLUMG00010012114
 protein coding gene Chr16:84038661-84081171 (+)
SPRET/EiJ ENSMSPG00010029285
 protein coding gene Chr16:85143514-85185567 (+)
WSB/EiJ ENSIUOG00005018622
 protein coding gene Chr16:84220189-84261896 (+)



Homology
more
  • Human Ortholog
    MAP3K7CL, MAP3K7 C-terminal like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAP3K7CL, MAP3K7 C-terminal like
  • Synonyms
    C21orf7, HC21ORF7, TAK1L, TAKL, TAKL-1, TAKL-2, TAKL-4
  • Links
    NCBI Gene ID: 56911
    UniProt: P57077

  • Chr Location
    21q21.3; chr21:29077060-29175889 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    132
  • cDNA Data
    9
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025610 Ensembl Gene Model | MGI Sequence Detail 42007 C57BL/6J ±  kb
transcript ENSMUST00000026700 Ensembl | MGI Sequence Detail 1652 Not Applicable  
polypeptide ENSMUSP00000026700 Ensembl | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 45
    Developmental Gene Expression 4
    Diseases 1
    Phenotypes 24
  • Earliest
    J:76842 Reymond A, et al., From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Genomics. 2001 Nov;78(1-2):46-54
  • Latest
    J:376814 Ranade SS, et al., Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21. Nature. 2025 Nov;647(8091):979-987
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory