Vps33b
Gene Detail

Symbol Name ID

Vps33b vacuolar protein sorting 33B (yeast) MGI:2446237

Synonyms

MGC:36556

Feature Type

protein coding gene

Genetic Map

Chromosome 7

45.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:80269649-80291579 bp, + strand From VEGA annotation of GRCm38   21931 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10261  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: vacuolar protein sorting-associated protein 33
Gene Tree: Vps33b

Human homologs

Human Homolog		VPS33B, vacuolar protein sorting 33 homolog B (yeast)
NCBI Gene ID		26276
neXtProt AC		NX_Q9H267
Human Chr (Location)		15q26.1; chr15:91541774-91565833 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human VPS33B

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	cellular membrane fusion, lysosome localization, ...
Component	cytoplasm, endosome, ...
Function	protein binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (27)    Tissues (5)    Images (16)
Theiler Stages: 23

Assay Type	Results
RNA in situ	27

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) cDNA(25)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000017577 (Evidence)
Ensembl Gene Model	ENSMUSG00000030534 (Evidence)
Entrez Gene	233405 (Evidence)
UniGene	322870
DFCI	TC1583814, TC1603100, TC1715226
DoTS	DT.101365097, DT.101365098, DT.55108123, DT.55207879, DT.91332194
NIA Mouse Gene Index	U008280
Consensus CDS Project	CCDS39997.1
International Mouse Knockout Project Status	Vps33b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017577	VEGA Gene Model | MGI Sequence Detail	21931	C57BL/6J
transcript	OTTMUST00000042739	VEGA | MGI Sequence Detail	2574	Not Applicable
polypeptide	OTTMUSP00000019195	VEGA | MGI Sequence Detail	617	Not Applicable

All sequences(43) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(213 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR027482	Sec1-like, domain 2
InterPro	IPR001619	Sec1-like protein
InterPro	IPR027121	Vacuolar protein sorting-associated protein 33
Protein Ontology	PR:000017332	vacuolar protein sorting-associated protein 33B

References

(Earliest) J:99274 Gissen P, et al., Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. Hum Mol Genet. 2005 May 15;14(10):1261-70
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)