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Phf13
Gene Detail
Symbol

Name
ID
Phf13
PHD finger protein 13
MGI:2446217
Synonyms
SPOC1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
82.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:151989633-151996258 bp, - strand
From VEGA annotation of GRCm38

  6626 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17822  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Phf13

Human
homologs
Human Homolog PHF13, PHD finger protein 13
NCBI Gene ID 148479
neXtProt AC  NX_Q86YI8
Human Synonyms  PHF5, SPOC1
Human Chr (Location)  1p36.31; chr1:6613696-6624033 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(4) Targeted(5)
Genomic Mutations involving Phf13 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap allele exhibit reduced male fertility over time associated with impaired spermatogonial stem cell differentiation and male germ cell apoptosis.
 
Interactions
Phf13 interacts with 300 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, cell division, ...
Component nucleus
Function chromatin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (113)    Tissues (61)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 104
RT-PCR 9
cDNA source data(54)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(56) cDNA(54) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000010357 (Evidence)
Ensembl Gene ModelENSMUSG00000047777 (Evidence)
Entrez Gene230936 (Evidence)
UniGene25582
DFCITC1579602
DoTSDT.490315, DT.101379585
NIA Mouse Gene IndexU025834
Consensus CDS ProjectCCDS51388.1
International Mouse Knockout Project StatusPhf13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010357 VEGA Gene Model | MGI Sequence Detail 6626 C57BL/6J ±  kb
transcript OTTMUST00000024139 VEGA | MGI Sequence Detail 3205 Not Applicable 
polypeptide OTTMUSP00000011094 VEGA | MGI Sequence Detail 296 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000012640 PHD finger protein 13
References
(Earliest) J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
(Latest) J:185876 Bordlein A, et al., SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis. J Cell Sci. 2011 Sep 15;124(Pt 18):3137-48
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory