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Phf13
Gene Detail
Symbol

Name
ID
Phf13
PHD finger protein 13
MGI:2446217
Synonyms
SPOC1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
82.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:151989633-151996258 bp, - strand
From VEGA annotation of GRCm38

  6626 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17822  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PHF13
Gene Tree: Phf13

Human
homologs
PHF13, PHD finger protein 13
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 148479
neXtProt AC: NX_Q86YI8

Human Synonyms: PHF5, SPOC1

Human Chr (Location): 1p36.31; chr1:6613696-6624033 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(4) Targeted(6)
Genomic Mutations involving Phf13 (3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap allele exhibit reduced male fertility over time associated with impaired spermatogonial stem cell differentiation and male germ cell apoptosis.
 
Interactions
Phf13 interacts with 299 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, cell division, ...
Component nucleus
Function chromatin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (113)    Tissues (61)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 104
RT-PCR 9
cDNA source data(54)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase phf13    NEW 
Molecular
reagents
All nucleic(56) cDNA(54) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000010357 (Evidence)
Ensembl Gene Model ENSMUSG00000047777 (Evidence)
Entrez Gene 230936 (Evidence)
UniGene 25582
DFCI TC1579602
DoTS DT.490315, DT.101379585
NIA Mouse Gene Index U025834
Consensus CDS Project CCDS51388.1
International Mouse Phenotyping Consortium Status Phf13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010357 VEGA Gene Model | MGI Sequence Detail 6626 C57BL/6J ±  kb
transcript OTTMUST00000024139 VEGA | MGI Sequence Detail 3205 Not Applicable 
polypeptide OTTMUSP00000011094 VEGA | MGI Sequence Detail 296 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000012640 PHD finger protein 13
References
(Earliest) J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
(Latest) J:185876 Bordlein A, et al., SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis. J Cell Sci. 2011 Sep 15;124(Pt 18):3137-48
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory