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Man1c1 Gene Detail
Summary
  • Symbol
    Man1c1
  • Name
    mannosidase, alpha, class 1C, member 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446214
    NCBI Gene: 230815
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:134289001-134431601 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 66.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4646 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446214
 protein coding gene Chr4:134289001-134432987 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028932
 protein coding gene Chr4:136924740-137073548 (-)
A/J MGP_AJ_G0028891
 protein coding gene Chr4:131165780-131310691 (-)
AKR/J MGP_AKRJ_G0028843
 protein coding gene Chr4:134930263-135076055 (-)
BALB/cJ MGP_BALBcJ_G0028915
 protein coding gene Chr4:131812632-131956238 (-)
C3H/HeJ MGP_C3HHeJ_G0028629
 protein coding gene Chr4:135173826-135320166 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029356
 protein coding gene Chr4:141865045-142015046 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026627
 protein coding gene Chr4:124220179-124361404 (-)
CAST/EiJ MGP_CASTEiJ_G0028061
 protein coding gene Chr4:133296076-133455542 (-)
CBA/J MGP_CBAJ_G0028594
 protein coding gene Chr4:145617323-145774033 (-)
DBA/2J MGP_DBA2J_G0028743
 protein coding gene Chr4:131586255-131727954 (-)
FVB/NJ MGP_FVBNJ_G0028710
 protein coding gene Chr4:130485699-130632444 (-)
LP/J MGP_LPJ_G0028842
 protein coding gene Chr4:137036759-137184925 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028736
 protein coding gene Chr4:150082890-150235844 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029394
 protein coding gene Chr4:135369403-135516886 (-)
PWK/PhJ MGP_PWKPhJ_G0027781
 protein coding gene Chr4:128320054-128465422 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027607
 protein coding gene Chr4:131184619-131343411 (-)
WSB/EiJ MGP_WSBEiJ_G0028139
 protein coding gene Chr4:135536811-135688561 (-)



Homology
more
  • Human Ortholog
    MAN1C1, mannosidase alpha class 1C member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAN1C1, mannosidase alpha class 1C member 1
  • Synonyms
    HMIC, MAN1A3, MAN1C, pp6318
  • Links
    NCBI Gene ID: 57134
    UniProt: Q9NR34

  • Chr Location
    1p36.11; chr1:25616791-25784450 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    134
  • cDNA Data
    10
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037306 Ensembl Gene Model | MGI Sequence Detail 142601 C57BL/6J ±  kb
transcript ENSMUST00000054096 Ensembl | MGI Sequence Detail 4715 Not Applicable  
polypeptide ENSMUSP00000050979 Ensembl | MGI Sequence Detail 625 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140336
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory