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Man1c1 Gene Detail
Summary
  • Symbol
    Man1c1
  • Name
    mannosidase, alpha, class 1C, member 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446214
    NCBI Gene: 230815
Location & Maps
more
  • Sequence Map
    Chr4:134561690-134704290 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      142601 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 66.88 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MAN1C1, mannosidase alpha class 1C member 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MAN1C1, mannosidase alpha class 1C member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HMIC, MAN1A3, MAN1C, pp6318
  • Links
    NCBI Gene ID: 57134
    neXtProt AC: NX_Q9NR34

  • Chr Location
    1p35; chr1:25617468-25786207 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Targeted
    3
  • Genomic Mutations
    3 involving Man1c1
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    24
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    151
  • Tissues
    134
  • cDNA Data
    9
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011212 VEGA Gene Model | MGI Sequence Detail 142601 C57BL/6J ±  kb
transcript OTTMUST00000026308 VEGA | MGI Sequence Detail 4715 Not Applicable  
polypeptide OTTMUSP00000012032 VEGA | MGI Sequence Detail 625 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1109 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
    3.2.1.-
  • InterPro Domains
    IPR001382 Glycoside hydrolase family 47
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140336
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory