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Cnot12 Gene Detail
Summary
  • Symbol
    Cnot12
  • Name
    CCR4-NOT transcription complex subunit 12
  • Synonyms
    mKIAA1741, TAB182, Tnks1bp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446193
    NCBI Gene: 228140
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:84878366-84903392 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 49.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    566 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446193
 protein coding gene Chr2:84878356-84903392 (+)
129S1/SvImJ ENSMUSG00200051173
 protein coding gene Chr2:81894891-81920023 (+)
A/J ENSMUSG00195051861
 protein coding gene Chr2:82007677-82032819 (+)
AKR/J ENSMUSG00220052284
 protein coding gene Chr2:81886405-81911547 (+)
BALB/cJ ENSMUSG00180054644
 protein coding gene Chr2:81935498-81960640 (+)
C3H/HeJ ENSMUSG00175052583
 protein coding gene Chr2:82075068-82100209 (+)
C57BL/6NJ ENSMUSG00215051509
 protein coding gene Chr2:81980006-82005140 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023740
 protein coding gene Chr2:79262135-79287207 (+)
CAST/EiJ ENSTCUG00005052346
 protein coding gene Chr2:81427827-81452946 (+)
CBA/J ENSMUSG00210027409
 protein coding gene Chr2:82102983-82128124 (+)
DBA/2J ENSMUSG00185056715
 protein coding gene Chr2:81931737-81956878 (+)
FVB/NJ ENSMUSG00205048612
 protein coding gene Chr2:81313857-81338994 (+)
JF1/MsJ ENSUMUG00000004770
 protein coding gene Chr2:81849949-81875066 (+)
LP/J ENSMUSG00230040846
 protein coding gene Chr2:83682811-83707954 (+)
NOD/ShiLtJ ENSMUSG00190045336
 protein coding gene Chr2:81972354-81997495 (+)
NZO/HlLtJ ENSMUSG00225001991
 protein coding gene Chr2:91567488-91592635 (+)
PWK/PhJ ENSLUMG00010047408
 protein coding gene Chr2:81866595-81891704 (+)
SPRET/EiJ ENSMSPG00010051390
 protein coding gene Chr2:83769270-83793444 (+)
WSB/EiJ ENSIUOG00005053255
 protein coding gene Chr2:81912916-81938045 (+)



Homology
more
  • Human Ortholog
    CNOT12, CCR4-NOT transcription complex subunit 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNOT12, CCR4-NOT transcription complex subunit 12
  • Synonyms
    TAB182, TNKS1BP1
  • Links
    NCBI Gene ID: 85456
    UniProt: Q9C0C2

  • Chr Location
    11q12.1; chr11:57299630-57325682 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    53
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033955 Ensembl Gene Model | MGI Sequence Detail 25027 C57BL/6J ±  kb
transcript ENSMUST00000111605 Ensembl | MGI Sequence Detail 5747 Not Applicable  
polypeptide ENSMUSP00000107232 Ensembl | MGI Sequence Detail 1720 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016498 182 kDa tankyrase-1-binding protein
    (term hierarchy)
  • InterPro Domains
    IPR032764 Tankyrase 1-binding protein, C-terminal
    IPR040006 Tankyrase 1-binding protein-like
  • GlyGen
    P58871 8 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (5 sites)
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 3
Other
Accession IDs
less
MGI:8330116
References
more
  • Summaries
    All 40
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:389864 Murata K, et al., A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain. Exp Anim. 2026 Jan 1;75(1):63-72
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory