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Nup188 Gene Detail
Summary
  • Symbol
    Nup188
  • Name
    nucleoporin 188
  • Synonyms
    mKIAA0169
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446190
    NCBI Gene: 227699
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30286422-30344263 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.49 cM, cytoband B
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    184 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446190
protein coding gene Chr2:30286397-30344266 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025564
protein coding gene Chr2:28504756-28569700 (+)
A/J MGP_AJ_G0025542
protein coding gene Chr2:27370807-27429767 (+)
AKR/J MGP_AKRJ_G0025511
protein coding gene Chr2:28302322-28361479 (+)
BALB/cJ MGP_BALBcJ_G0025538
protein coding gene Chr2:27495011-27553166 (+)
C3H/HeJ MGP_C3HHeJ_G0025299
protein coding gene Chr2:28231226-28293413 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025983
protein coding gene Chr2:29440632-29505457 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023391
protein coding gene Chr2:26149487-26207705 (+)
CAST/EiJ MGP_CASTEiJ_G0024761
protein coding gene Chr2:28124732-28189225 (+)
CBA/J MGP_CBAJ_G0025276
protein coding gene Chr2:30448745-30509194 (+)
DBA/2J MGP_DBA2J_G0025409
protein coding gene Chr2:27160590-27218477 (+)
FVB/NJ MGP_FVBNJ_G0025372
protein coding gene Chr2:26979391-27037594 (+)
LP/J MGP_LPJ_G0025495
protein coding gene Chr2:28413654-28475183 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025402
protein coding gene Chr2:30329079-30389444 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026041
protein coding gene Chr2:28218336-28278093 (+)
PWK/PhJ MGP_PWKPhJ_G0024508
protein coding gene Chr2:26999230-27058839 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024308
protein coding gene Chr2:28333921-28395089 (+)
WSB/EiJ MGP_WSBEiJ_G0024829
protein coding gene Chr2:28342430-28405289 (+)



Homology
more
  • Human Ortholog
    NUP188, nucleoporin 188
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP188, nucleoporin 188
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hNup188, KIAA0169
  • Links
    NCBI Gene ID: 23511
    neXtProt AC: NX_Q5SRE5
    UniProt: Q5SRE5

  • Chr Location
    9q34.11; chr9:128947693-129007096 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 45683
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NUP188
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 227699 NCBI Gene Model | MGI Sequence Detail 57842 C57BL/6J ±  kb
transcript NM_198304 RefSeq | MGI Sequence Detail 5700 C57BL/6  
polypeptide Q6ZQH8 UniProt | EBI | MGI Sequence Detail 1759 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 134
    cDNA 134

    Microarray probesets 6
Other
Accession IDs
less
MGI:1927640
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory