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Spryd3 Gene Detail
Summary
  • Symbol
    Spryd3
  • Name
    SPRY domain containing 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446175
    NCBI Gene: 223918
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102116528-102136234 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 57.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446175
protein coding gene Chr15:102116526-102136243 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022399
protein coding gene Chr15:104256755-104287389 (-)
A/J MGP_AJ_G0022361
protein coding gene Chr15:100176048-100194372 (-)
AKR/J MGP_AKRJ_G0022336
protein coding gene Chr15:103207061-103226100 (-)
BALB/cJ MGP_BALBcJ_G0022365
protein coding gene Chr15:100219380-100238964 (-)
C3H/HeJ MGP_C3HHeJ_G0022132
protein coding gene Chr15:103278314-103300135 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022814
protein coding gene Chr15:108145029-108166391 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020337
protein coding gene Chr15:95951736-95970436 (-)
CAST/EiJ MGP_CASTEiJ_G0021658
protein coding gene Chr15:104134988-104155063 (-)
CBA/J MGP_CBAJ_G0022101
protein coding gene Chr15:111921477-111945790 (-)
DBA/2J MGP_DBA2J_G0022232
protein coding gene Chr15:99462764-99483137 (-)
FVB/NJ MGP_FVBNJ_G0022208
protein coding gene Chr15:98518333-98539998 (-)
LP/J MGP_LPJ_G0022301
protein coding gene Chr15:104422035-104446043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022230
protein coding gene Chr15:115521937-115541509 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022826
protein coding gene Chr15:103226855-103248116 (-)
PWK/PhJ MGP_PWKPhJ_G0021398
protein coding gene Chr15:99611392-99630208 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021230
protein coding gene Chr15:103074130-103092486 (-)
WSB/EiJ MGP_WSBEiJ_G0021708
protein coding gene Chr15:103855111-103874299 (-)



Homology
more
  • Human Ortholog
    SPRYD3, SPRY domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SPRYD3, SPRY domain containing 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 84926
    neXtProt AC: NX_Q8NCJ5
    UniProt: Q8NCJ5

  • Chr Location
    12q13.13; chr12:53064316-53079420 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13138
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SPRYD3
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036966 Ensembl Gene Model | MGI Sequence Detail 19707 C57BL/6J ±  kb
transcript ENSMUST00000154032 Ensembl | MGI Sequence Detail 2456 Not Applicable  
polypeptide ENSMUSP00000121493 Ensembl | MGI Sequence Detail 442 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001870 B30.2/SPRY domain
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR003877 SPRY domain
    IPR035783 SPRY domain-containing protein 3, SPRY domain
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Diseases 1
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory