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Farp1 Gene Detail
Summary
  • Symbol
    Farp1
  • Name
    FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
  • Synonyms
    Cdep
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446173
    NCBI Gene: 223254
  • Gene Overview
    MyGene.info: FARP1
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:121035200-121283744 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 64.86 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2612 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446173
 protein coding gene Chr14:121035200-121283744 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021660
 protein coding gene Chr14:118792646-119067617 (+)
A/J MGP_AJ_G0021620
 protein coding gene Chr14:114236296-114486518 (+)
AKR/J MGP_AKRJ_G0021596
 protein coding gene Chr14:117922253-118186609 (+)
BALB/cJ MGP_BALBcJ_G0021626
 protein coding gene Chr14:114773434-115023253 (+)
C3H/HeJ MGP_C3HHeJ_G0021404
 protein coding gene Chr14:117813852-118079645 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022066
 protein coding gene Chr14:123381411-123668476 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019604
 protein coding gene Chr14:110135967-110382521 (+)
CAST/EiJ MGP_CASTEiJ_G0020919
 protein coding gene Chr14:115698714-115966651 (+)
CBA/J MGP_CBAJ_G0021372
 protein coding gene Chr14:128085083-128366412 (+)
DBA/2J MGP_DBA2J_G0021495
 protein coding gene Chr14:114108027-114358948 (+)
FVB/NJ MGP_FVBNJ_G0021473
 protein coding gene Chr14:112430181-112685918 (+)
LP/J MGP_LPJ_G0021563
 protein coding gene Chr14:119763869-120033270 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021500
 protein coding gene Chr14:133123953-133397163 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022089
 protein coding gene Chr14:117466631-117739910 (+)
PWK/PhJ MGP_PWKPhJ_G0020663
 protein coding gene Chr14:111145966-111397294 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020501
 protein coding gene Chr14:113695987-113950536 (+)
WSB/EiJ MGP_WSBEiJ_G0020975
 protein coding gene Chr14:118181138-118448053 (+)



Homology
more
  • Human Ortholog
    FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDEP, FARP1-IT1, PLEKHC2, PPP1R75
  • Links
    NCBI Gene ID: 10160
    neXtProt AC: NX_Q9Y4F1
    UniProt: Q9Y4F1

  • Chr Location
    13q32.2; chr13:98142562-98449773 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 38098
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FARP1
  • Gene Tree
    Farp1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    42
  • Tissues
    28
  • cDNA Data
    143
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223254 NCBI Gene Model | MGI Sequence Detail 248545 C57BL/6J ±  kb
transcript NM_134082 RefSeq | MGI Sequence Detail 4857 C57BL/6  
polypeptide F8VPU2 UniProt | EBI | MGI Sequence Detail 1048 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 143
    cDNA 143

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145808
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/08/2019
MGI 6.13 		The Jackson Laboratory