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Scml4 Gene Detail
Summary
  • Symbol
    Scml4
  • Name
    sex comb on midleg-like 4 (Drosophila)
  • Synonyms
    MGC:49264
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446140
    NCBI Gene: 268297
Location & Maps
more
  • Sequence Map
    Chr10:42860370-42960780 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      100411 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 22.89 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SCML4, sex comb on midleg-like 4 (Drosophila)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCML4, sex comb on midleg-like 4 (Drosophila)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ47M23.1
  • Links
    NCBI Gene ID: 256380
    neXtProt AC: NX_Q8N228

  • Chr Location
    6q21; chr6:107697297-107848659 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18262
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SCML4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Scml4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017273 VEGA Gene Model | MGI Sequence Detail 100411 C57BL/6J ±  kb
transcript OTTMUST00000041827 VEGA | MGI Sequence Detail 4885 Not Applicable  
polypeptide OTTMUSP00000018808 VEGA | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    603 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000014521 sex comb on midleg-like protein 4
  • InterPro Domains
    IPR021987 Protein of unknown function DUF3588
    IPR001660 Sterile alpha motif domain
    IPR013761 Sterile alpha motif/pointed domain
Molecular
Reagents
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  • All nucleic 35
    cDNA 35

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory