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Mfsd4b5 Gene Detail
Summary
  • Symbol
    Mfsd4b5
  • Name
    major facilitator superfamily domain containing 4B5
  • Synonyms
    BC021785
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446139
    NCBI Gene: 215928
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:39958061-39986646 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 21.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446139
protein coding gene Chr10:39958061-39986646 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017157
protein coding gene Chr10:38499424-38530458 (-)
A/J MGP_AJ_G0017134
protein coding gene Chr10:37460904-37489793 (-)
AKR/J MGP_AKRJ_G0017094
protein coding gene Chr10:37987975-38021655 (-)
BALB/cJ MGP_BALBcJ_G0017097
protein coding gene Chr10:37528175-37559135 (-)
C3H/HeJ MGP_C3HHeJ_G0016917
protein coding gene Chr10:38313532-38342498 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017555
protein coding gene Chr10:39674543-39707331 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015251
protein coding gene Chr10:35451796-35477489 (-)
CAST/EiJ MGP_CASTEiJ_G0016496
protein coding gene Chr10:38487818-38514944 (-)
CBA/J MGP_CBAJ_G0016891
protein coding gene Chr10:41503696-41534221 (-)
DBA/2J MGP_DBA2J_G0016996
protein coding gene Chr10:36979914-37008205 (-)
FVB/NJ MGP_FVBNJ_G0016991
protein coding gene Chr10:36486439-36514501 (-)
LP/J MGP_LPJ_G0017073
protein coding gene Chr10:38465173-38496367 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017021
protein coding gene Chr10:42344272-42375826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017592
protein coding gene Chr10:37978018-38008155 (-)
PWK/PhJ MGP_PWKPhJ_G0016276
protein coding gene Chr10:36834757-36863074 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016060
protein coding gene Chr10:37783592-37819728 (-)
WSB/EiJ MGP_WSBEiJ_G0016559
protein coding gene Chr10:38258725-38291734 (-)



Homology
more
  • Human Ortholog
    MFSD4B, major facilitator superfamily domain containing 4B
  • Vertebrate Orthologs
    2
  • Human Ortholog
    MFSD4B, major facilitator superfamily domain containing 4B
    Orthology source: HGNC
  • Synonyms
    KIAA1919, NaGLT1
  • Links
    NCBI Gene ID: 91749
    neXtProt AC: NX_Q5TF39
    UniProt: Q5TF39

  • Chr Location
    6q21; chr6:111259279-111280005 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 215928 NCBI Gene Model | MGI Sequence Detail 28586 C57BL/6J ±  kb
transcript NM_001113385 RefSeq | MGI Sequence Detail 3551 C57BL/6  
polypeptide NP_001106856 RefSeq | MGI Sequence Detail 479 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR003445 Cation transporter
    IPR011701 Major facilitator superfamily
    IPR020846 Major facilitator superfamily domain
    IPR036259 MFS transporter superfamily
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory