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Cracr2b Gene Detail
Summary
  • Symbol
    Cracr2b
  • Name
    calcium release activated channel regulator 2B
  • Synonyms
    6330520A15Rik, Efcab4a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446129
    NCBI Gene: 213573
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141041007-141046526 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446129
 protein coding gene Chr7:141041007-141046526 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033233
 protein coding gene Chr7:146652396-146659524 (+)
A/J MGP_AJ_G0033215
 protein coding gene Chr7:142458052-142464676 (+)
AKR/J MGP_AKRJ_G0033147
 protein coding gene Chr7:146410110-146415626 (+)
BALB/cJ MGP_BALBcJ_G0033216
 protein coding gene Chr7:142203560-142209102 (+)
C3H/HeJ MGP_C3HHeJ_G0032930
 protein coding gene Chr7:146145507-146151019 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033727
 protein coding gene Chr7:152005228-152010683 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030700
 protein coding gene Chr7:143666306-143671925 (+)
CAST/EiJ MGP_CASTEiJ_G0032260
 protein coding gene Chr7:138458248-138465024 (+)
CBA/J MGP_CBAJ_G0032902
 protein coding gene Chr7:157164973-157170489 (+)
DBA/2J MGP_DBA2J_G0033054
 protein coding gene Chr7:140403543-140409060 (+)
FVB/NJ MGP_FVBNJ_G0033007
 protein coding gene Chr7:140317821-140323974 (+)
LP/J MGP_LPJ_G0033149
 protein coding gene Chr7:148146480-148152012 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033040
 protein coding gene Chr7:157798135-157804817 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033747
 protein coding gene Chr7:145367913-145373424 (+)
PWK/PhJ MGP_PWKPhJ_G0031964
 protein coding gene Chr7:133688662-133694191 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031811
 protein coding gene Chr7:132201797-132207337 (+)
WSB/EiJ MGP_WSBEiJ_G0032371
 protein coding gene Chr7:146316357-146321970 (+)



Homology
more
  • Human Ortholog
    CRACR2B, calcium release activated channel regulator 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRACR2B, calcium release activated channel regulator 2B
  • Synonyms
    EFCAB4A
  • Links
    NCBI Gene ID: 283229
    UniProt: Q8N4Y2

  • Chr Location
    11p15.5; chr11:826144-831991 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    38
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 213573 NCBI Gene Model | MGI Sequence Detail 5520 C57BL/6J ±  kb
transcript NM_001025103 RefSeq | MGI Sequence Detail 1687 Not Specified  
polypeptide Q80ZJ8 UniProt | EBI | MGI Sequence Detail 394 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 2
Other
Accession IDs
less
MGI:1925677
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory