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Cracr2b Gene Detail
Summary
  • Symbol
    Cracr2b
  • Name
    calcium release activated channel regulator 2B
  • Synonyms
    6330520A15Rik, Efcab4a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446129
    NCBI Gene: 213573
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141461094-141466613 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446129
 protein coding gene Chr7:141460870-141466613 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033233
 protein coding gene Chr7:146652396-146659524 (+)
A/J MGP_AJ_G0033215
 protein coding gene Chr7:142458052-142464676 (+)
AKR/J MGP_AKRJ_G0033147
 protein coding gene Chr7:146410110-146415626 (+)
BALB/cJ MGP_BALBcJ_G0033216
 protein coding gene Chr7:142203560-142209102 (+)
C3H/HeJ MGP_C3HHeJ_G0032930
 protein coding gene Chr7:146145507-146151019 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033727
 protein coding gene Chr7:152005228-152010683 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030700
 protein coding gene Chr7:143666306-143671925 (+)
CAST/EiJ MGP_CASTEiJ_G0032260
 protein coding gene Chr7:138458248-138465024 (+)
CBA/J MGP_CBAJ_G0032902
 protein coding gene Chr7:157164973-157170489 (+)
DBA/2J MGP_DBA2J_G0033054
 protein coding gene Chr7:140403543-140409060 (+)
FVB/NJ MGP_FVBNJ_G0033007
 protein coding gene Chr7:140317821-140323974 (+)
LP/J MGP_LPJ_G0033149
 protein coding gene Chr7:148146480-148152012 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033040
 protein coding gene Chr7:157798135-157804817 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033747
 protein coding gene Chr7:145367913-145373424 (+)
PWK/PhJ MGP_PWKPhJ_G0031964
 protein coding gene Chr7:133688662-133694191 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031811
 protein coding gene Chr7:132201797-132207337 (+)
WSB/EiJ MGP_WSBEiJ_G0032371
 protein coding gene Chr7:146316357-146321970 (+)



Homology
more
  • Human Ortholog
    CRACR2B, calcium release activated channel regulator 2B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CRACR2B, calcium release activated channel regulator 2B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFCAB4A
  • Links
    NCBI Gene ID: 283229
    neXtProt AC: NX_Q8N4Y2
    UniProt: Q8N4Y2

  • Chr Location
    11p15.5; chr11:825558-831991 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    38
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048200 Ensembl Gene Model | MGI Sequence Detail 5520 C57BL/6J ±  kb
transcript ENSMUST00000053670 Ensembl | MGI Sequence Detail 1698 Not Applicable  
polypeptide ENSMUSP00000055899 Ensembl | MGI Sequence Detail 394 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 2
Other
Accession IDs
less
MGI:1925677
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/10/2019
MGI 6.14 		The Jackson Laboratory