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Suox
Gene Detail
Symbol

Name
ID
Suox
sulfite oxidase
MGI:2446117
Synonyms
MGC:28458, SO
Feature Type
protein coding gene
Genetic Map
Chromosome 10
77.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:128669887-128673918 bp, - strand
From NCBI annotation of GRCm38

  4032 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:394  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: sulfite oxidase
Gene Tree: Suox

Human
homologs
Human Homolog SUOX, sulfite oxidase
NCBI Gene ID 6821
neXtProt AC  NX_P51687
Human Chr (Location)  12q13.2; chr12:55997259-56005525 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SUOX
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Suox interacts with 101 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process, response to nutrient
Component cytosol, mitochondrial intermembrane space, ...
Function electron carrier activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (93)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(48) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000049858 (Evidence)
Entrez Gene211389 (Evidence)
UniGene23352
DFCITC1577798
DoTSDT.530636
NIA Mouse Gene IndexU032370
EC1.8.3.1
Consensus CDS ProjectCCDS24285.1
International Mouse Knockout Project StatusSuox
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 211389 NCBI Gene Model | MGI Sequence Detail 4032 C57BL/6J ±  kb
transcript NM_173733 RefSeq | MGI Sequence Detail 2349 Not Specified 
polypeptide Q8R086 UniProt | EBI | MGI Sequence Detail 546 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018506 Cytochrome b5, heme-binding site
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
InterPro IPR008335 Eukaryotic molybdopterin oxidoreductase
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR005066 Moybdenum cofactor oxidoreductase, dimerisation
InterPro IPR000572 Oxidoreductase, molybdopterin-binding domain
InterPro IPR022407 Oxidoreductase, molybdopterin binding site
Protein Ontology PR:000015833 sulfite oxidase, mitochondrial
Graphical View of Protein Domain Structure
References
(Earliest) J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
(Latest) J:199765 Klein JM, et al., Cofactor-dependent maturation of mammalian sulfite oxidase links two mitochondrial import pathways. J Cell Sci. 2012 Oct 15;125(Pt 20):4876-85
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory