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Suox Gene Detail
Summary
  • Symbol
    Suox
  • Name
    sulfite oxidase
  • Synonyms
    MGC:28458, SO
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446117
    NCBI Gene: 211389
  • Gene Overview
    MyGene.info: SUOX
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128669887-128673918 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 77.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446117
 protein coding gene Chr10:128669887-128674073 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017876
 protein coding gene Chr10:132434969-132439000 (-)
A/J MGP_AJ_G0017851
 protein coding gene Chr10:127117655-127121686 (-)
AKR/J MGP_AKRJ_G0017814
 protein coding gene Chr10:130835941-130839972 (-)
BALB/cJ MGP_BALBcJ_G0017815
 protein coding gene Chr10:127485503-127489534 (-)
C3H/HeJ MGP_C3HHeJ_G0017638
 protein coding gene Chr10:131002717-131006748 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018270
 protein coding gene Chr10:136911920-136915951 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015948
 protein coding gene Chr10:121034428-121038465 (-)
CAST/EiJ MGP_CASTEiJ_G0017199
 protein coding gene Chr10:131724220-131728250 (-)
CBA/J MGP_CBAJ_G0017608
 protein coding gene Chr10:142489650-142493681 (-)
DBA/2J MGP_DBA2J_G0017714
 protein coding gene Chr10:126179153-126183184 (-)
FVB/NJ MGP_FVBNJ_G0017709
 protein coding gene Chr10:125094542-125098573 (-)
LP/J MGP_LPJ_G0017788
 protein coding gene Chr10:133027279-133031310 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017737
 protein coding gene Chr10:145063879-145067910 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018310
 protein coding gene Chr10:130940286-130944317 (-)
PWK/PhJ MGP_PWKPhJ_G0016984
 protein coding gene Chr10:126434227-126438258 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016773
 protein coding gene Chr10:130053490-130057518 (-)
WSB/EiJ MGP_WSBEiJ_G0017258
 protein coding gene Chr10:131161078-131165109 (-)



Homology
more
  • Human Ortholog
    SUOX, sulfite oxidase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SUOX, sulfite oxidase
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 6821
    neXtProt AC: NX_P51687
    UniProt: P51687

  • Chr Location
    12q13.2; chr12:55996776-56005525 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human SUOX associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    93
  • cDNA Data
    49
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211389 NCBI Gene Model | MGI Sequence Detail 4032 C57BL/6J ±  kb
transcript NM_173733 RefSeq | MGI Sequence Detail 2349 Not Specified  
polypeptide Q8R086 UniProt | EBI | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015833 sulfite oxidase, mitochondrial
    (term hierarchy)
  • EC
    1.8.3.1
  • InterPro Domains
    IPR018506 Cytochrome b5, heme-binding site
    IPR001199 Cytochrome b5-like heme/steroid binding domain
    IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily
    IPR008335 Eukaryotic molybdopterin oxidoreductase
    IPR014756 Immunoglobulin E-set
    IPR005066 Moybdenum cofactor oxidoreductase, dimerisation
    IPR000572 Oxidoreductase, molybdopterin-binding domain
    IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily
    IPR022407 Oxidoreductase, molybdopterin binding site
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
  • Latest
    J:226108 Belaidi AA, et al., Oxygen reactivity of mammalian sulfite oxidase provides a concept for the treatment of sulfite oxidase deficiency. Biochem J. 2015 Jul 15;469(2):211-21
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/19/2021
MGI 6.16 		The Jackson Laboratory