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Suox
Gene Detail
Symbol

Name
ID
Suox
sulfite oxidase
MGI:2446117
Synonyms
MGC:28458, SO
Feature Type
protein coding gene
Genetic Map
Chromosome 10
77.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:128669887-128673918 bp, - strand
From NCBI annotation of GRCm38

  4032 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:394  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SUOX
Protein SuperFamily: sulfite oxidase
Gene Tree: Suox

Human
homologs
SUOX, sulfite oxidase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 6821
neXtProt AC: NX_P51687

Human Chr (Location): 12q13.2; chr12:55997259-56005525 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SUOX

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Suox interacts with 101 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process nitrate assimilation, oxidation-reduction process, ...
Component cytosol, mitochondrial intermembrane space, ...
Function heme binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (93)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(48)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase suox    NEW 
Molecular
reagents
All nucleic(49) cDNA(48) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000049858 (Evidence)
Entrez Gene 211389 (Evidence)
UniGene 23352
DFCI TC1577798
DoTS DT.530636
NIA Mouse Gene Index U032370
EC 1.8.3.1
Consensus CDS Project CCDS24285.1
International Mouse Phenotyping Consortium Status Suox
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 211389 NCBI Gene Model | MGI Sequence Detail 4032 C57BL/6J ±  kb
transcript NM_173733 RefSeq | MGI Sequence Detail 2349 Not Specified 
polypeptide Q8R086 UniProt | EBI | MGI Sequence Detail 546 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018506 Cytochrome b5, heme-binding site
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
InterPro IPR008335 Eukaryotic molybdopterin oxidoreductase
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR005066 Moybdenum cofactor oxidoreductase, dimerisation
InterPro IPR000572 Oxidoreductase, molybdopterin-binding domain
InterPro IPR022407 Oxidoreductase, molybdopterin binding site
Protein Ontology PR:000015833 sulfite oxidase, mitochondrial
Graphical View of Protein Domain Structure
References
(Earliest) J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
(Latest) J:199765 Klein JM, et al., Cofactor-dependent maturation of mammalian sulfite oxidase links two mitochondrial import pathways. J Cell Sci. 2012 Oct 15;125(Pt 20):4876-85
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory