Suox MGI Mouse Gene Detail - MGI:2446117

Suox Gene Detail

Symbol

Suox
Name

sulfite oxidase
Synonyms

MGC:28458, SO

Feature Type

protein coding gene
IDs

MGI:2446117
NCBI Gene: 211389
Gene Overview

MyGene.info: SUOX

Sequence Map

Chr10:128669887-128673918 bp, - strand
From NCBI annotation of GRCm38

Mouse Genome Browser
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Sequence

4032 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 77.12 cM
Mapping Data

1 experiment

Human Ortholog

SUOX, sulfite oxidase

Vertebrate Orthologs

9

Human Ortholog

SUOX, sulfite oxidase
Orthology source: HomoloGene, HGNC
Links

HGNC:11460

NCBI Gene ID: 6821

neXtProt AC: NX_P51687
Chr Location

12q13.2; chr12:55997259-56005525 (+) GRCh38.p2

HomoloGene

Vertebrate Homology Class 394
1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 zebrafish;1 frog, western clawed
HCOP

human homology predictions: SUOX
Protein SuperFamily

sulfite oxidase
Gene Tree

Suox

Diseases

1 with human SUOX associations

				Human Disease	Mouse Models
				Sulfocysteinuria OMIM: 272300

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

2
Targeted

2
Incidental Mutations

Mutagenetix , APF

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All GO Annotations

14
GO References

5

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

94
Tissues

93
cDNA Data

48
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO
Other Vertebrate Links

Xenbase suox

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Suox interacts with 101 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

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All Sequences

25
RefSeq

2
UniProt

1
CCDS

CCDS24285.1
UniGene

23352

Ensembl

ENSMUSG00000049858 (Evidence)
NCBI Gene

211389

			Length	Strain/Species	Flank
genomic	211389	NCBI Gene Model \| MGI Sequence Detail	4032	C57BL/6J	± kb
transcript	NM_173733	RefSeq \| MGI Sequence Detail	2349	Not Specified
polypeptide	Q8R086	UniProt \| EBI \| MGI Sequence Detail	546	Not Applicable

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SNPs within 2kb

46 from dbSNP Build 142

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UniProt

1 Sequence
Protein Ontology

PR:000015833 sulfite oxidase, mitochondrial
EC

1.8.3.1
InterPro Domains

IPR018506 Cytochrome b5, heme-binding site

IPR001199 Cytochrome b5-like heme/steroid binding domain

IPR008335 Eukaryotic molybdopterin oxidoreductase

IPR014756 Immunoglobulin E-set

IPR005066 Moybdenum cofactor oxidoreductase, dimerisation

IPR000572 Oxidoreductase, molybdopterin-binding domain

IPR022407 Oxidoreductase, molybdopterin binding site

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All nucleic 49

cDNA 48

Primer pair 1

Microarray probesets 3

Summaries

All 29

Developmental Gene Expression 2

Gene Ontology 5

Phenotypes 2
Earliest

J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
Latest

J:226108 Belaidi AA, et al., Oxygen reactivity of mammalian sulfite oxidase provides a concept for the treatment of sulfite oxidase deficiency. Biochem J. 2015 Jul 15;469(2):211-21

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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