Suox
Gene Detail

Symbol

Name
ID

Suox
sulfite oxidase
MGI:2446117

Synonyms

MGC:28458, SO

Feature Type

protein coding gene

Genetic Map

Chromosome 10
77.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:128669887-128673918 bp, - strand From NCBI annotation of GRCm38   4032 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:394  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: sulfite oxidase
Gene Tree: Suox

Human
homologs

Human Homolog		SUOX, sulfite oxidase
NCBI Gene ID		6821
neXtProt AC		NX_P51687
Human Chr (Location)		12q13.2; chr12:55997259-56005525 (+)  GRCh38
Disease Associations		(1) Diseases Associated with Human SUOX

Mutations,
alleles, and
phenotypes

All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Suox interacts with 101 markers (Mir9-1, Mir9-2, Mir9-3, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (14 annotations)

Process	oxidation-reduction process, response to nutrient
Component	cytosol, mitochondrial intermembrane space, ...
Function	electron carrier activity, heme binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (94)    Tissues (93)    Images (16)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	94

cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(49) cDNA(48) Primer pair(1)
Microarray probesets(3)

Other database
links

Ensembl Gene Model	ENSMUSG00000049858 (Evidence)
Entrez Gene	211389 (Evidence)
UniGene	23352
DFCI	TC1577798
DoTS	DT.530636
NIA Mouse Gene Index	U032370
EC	1.8.3.1
Consensus CDS Project	CCDS24285.1
International Mouse Knockout Project Status	Suox

Sequences

Length	Strain/Species
genomic	211389	NCBI Gene Model | MGI Sequence Detail	4032	C57BL/6J
transcript	NM_173733	RefSeq | MGI Sequence Detail	2349	Not Specified
polypeptide	Q8R086	UniProt | EBI | MGI Sequence Detail	546	Not Applicable

All sequences(30) RefSeq(4) UniProt(1)

Polymorphisms

SNPs within 2kb(46 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR018506	Cytochrome b5, heme-binding site
InterPro	IPR001199	Cytochrome b5-like heme/steroid binding domain
InterPro	IPR008335	Eukaryotic molybdopterin oxidoreductase
InterPro	IPR014756	Immunoglobulin E-set
InterPro	IPR005066	Moybdenum cofactor oxidoreductase, dimerisation
InterPro	IPR000572	Oxidoreductase, molybdopterin-binding domain
InterPro	IPR022407	Oxidoreductase, molybdopterin binding site
Protein Ontology	PR:000015833	sulfite oxidase, mitochondrial

Graphical View of Protein Domain Structure

References

(Earliest) J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
(Latest) J:199765 Klein JM, et al., Cofactor-dependent maturation of mammalian sulfite oxidase links two mitochondrial import pathways. J Cell Sci. 2012 Oct 15;125(Pt 20):4876-85
All references(33)