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Wnt9a
Gene Detail
Symbol

Name
ID
Wnt9a
wingless-type MMTV integration site family, member 9A
MGI:2446084
Synonyms
Wnt14
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:59306928-59333552 bp, + strand
From VEGA annotation of GRCm38

  26625 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20722  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: WNT9A
Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt9a

Human
homologs
WNT9A, wingless-type MMTV integration site family, member 9A
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 7483
neXtProt AC: NX_O14904

Human Synonyms: WNT14

Human Chr (Location): 1q42; chr1:227918658-227947975 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from CvDC )
 
Homozygous inactivation of this gene results in neonatal lethality, altered chondrocyte maturation, cranial defects, and skeletal abnormalities including shortened appendicular long bones, partial joint fusions of carpal and tarsal elements, and chondroid metaplasia in synovial and fibrous joints.
 
Interactions
Wnt9a interacts with 269 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process anatomical structure development, canonical Wnt signaling pathway, ...
Component extracellular exosome, extracellular region, ...
Function frizzled binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (43 records)
Data Summary: Results (375)    Tissues (346)    Images (45)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 358
RT-PCR 17
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA WNT9A ; Xenbase wnt9a ; ZFIN wnt9a    NEW 
Molecular
reagents
All nucleic(14) cDNA(7) Primer pair(4) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000005790 (Evidence)
Ensembl Gene Model ENSMUSG00000000126 (Evidence)
Entrez Gene 216795 (Evidence)
UniGene 218794
DFCI TC1599379, TC1582785
DoTS DT.101721824
NIA Mouse Gene Index U012680
Consensus CDS Project CCDS36169.1
International Mouse Phenotyping Consortium Status Wnt9a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005790 VEGA Gene Model | MGI Sequence Detail 26625 C57BL/6J ±  kb
transcript OTTMUST00000012816 VEGA | MGI Sequence Detail 3320 Not Applicable 
polypeptide OTTMUSP00000005960 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(217 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR013303 Wnt-9a protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017452 protein Wnt-9a
References
(Earliest) J:76632 Katoh M, Molecular cloning and expression of mouse Wnt14, and structural comparison between mouse Wnt14-Wnt3a gene cluster and human WNT14-WNT3A gene cluster. Int J Mol Med. 2002 Mar;9(3):221-7
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(71)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory