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Serpinb1c
Gene Detail
 Symbol
Name
ID
Serpinb1c
serine (or cysteine) peptidase inhibitor, clade B, member 1c
MGI:2445363
Synonyms EIC, ovalbumin
Feature Type protein coding gene
Genetic Map
Chromosome 13
13.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:32881833-32898161 bp, - strand
From VEGA annotation of GRCm38

  16329 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137840  Vertebrate Homology Class
1 mouse

Protein SuperFamily: serpin
Gene Tree: Serpinb1c

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb1c interacts with 12 markers (Mir34b, Mir34c, Mir130b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component cytoplasm, extracellular space
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (1)    Images (22)
Theiler Stages: 23
Assay TypeResults
RNA in situ 22
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) Genomic(3) cDNA(5)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000000695 (Evidence)
Ensembl Gene ModelENSMUSG00000079049 (Evidence)
Entrez Gene380839 (Evidence)
DFCITC1589741, TC1626579
DoTSDT.55190678, DT.87070543
NIA Mouse Gene IndexU047584
Consensus CDS ProjectCCDS26429.1
International Mouse Knockout Project StatusSerpinb1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000695 VEGA Gene Model | MGI Sequence Detail 16329 C57BL/6J ±  kb
transcript OTTMUST00000001327 VEGA | MGI Sequence Detail 1184 Not Applicable 
polypeptide OTTMUSP00000000624 VEGA | MGI Sequence Detail 375 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(57 from dbSNP Build 137)    SNPs within 2kb including multiple locations(59)
Protein-related
information
ResourceIDDescription
InterPro IPR015557 Protease inhibitor I4, serpin B1
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015943 leukocyte elastase inhibitor C
References (Earliest) J:75161 Kaiserman D, et al., Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics. 2002 Mar;79(3):349-62
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory