Serpinb1c
Gene Detail

Symbol Name ID

Serpinb1c serine (or cysteine) peptidase inhibitor, clade B, member 1c MGI:2445363

Synonyms

EIC, ovalbumin

Feature Type

protein coding gene

Genetic Map

Chromosome 13

13.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr13:32881833-32898161 bp, - strand From VEGA annotation of GRCm38   16329 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: serpin
Gene Tree: Serpinb1c

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	cytoplasm, extracellular space
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (1)    Images (22)
Theiler Stages: 23

Assay Type	Results
RNA in situ	22

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) Genomic(3) cDNA(5)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000000695 (Evidence)
Ensembl Gene Model	ENSMUSG00000079049 (Evidence)
Entrez Gene	380839 (Evidence)
DFCI	TC1589741, TC1626579
DoTS	DT.55190678, DT.87070543
NIA Mouse Gene Index	U047584
Consensus CDS Project	CCDS26429.1
International Mouse Knockout Project Status	Serpinb1c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000000695	VEGA Gene Model | MGI Sequence Detail	16329	C57BL/6J
transcript	OTTMUST00000001327	VEGA | MGI Sequence Detail	1184	Not Applicable
polypeptide	OTTMUSP00000000624	VEGA | MGI Sequence Detail	375	Not Applicable

All sequences(26) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(57 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015557	Protease inhibitor I4, serpin B1
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000015943	leukocyte elastase inhibitor C

References

(Earliest) J:75161 Kaiserman D, et al., Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics. 2002 Mar;79(3):349-62
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(21)