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Tmem184b Gene Detail
Summary
  • Symbol
    Tmem184b
  • Name
    transmembrane protein 184b
  • Synonyms
    4732495E13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445179
    NCBI Gene: 223693
  • Gene Overview
    MyGene.info: TMEM184B
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:79360684-79403303 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42620 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM184B, transmembrane protein 184B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM184B, transmembrane protein 184B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C22orf5, FM08, HS5O6A, HSPC256
  • Links
    NCBI Gene ID: 25829
    neXtProt AC: NX_Q9Y519
    UniProt: Q9Y519

  • Chr Location
    22q13.1; chr22:38216045-38273034 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene-trapped allele exhibit delayed axon degeneration following peripheral nerve injury, progressive structural abnormalities at neuromuscular synapses, swellings within sensory terminals, sensory-motor dysfunction, and abnormal autophagy.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 223693 NCBI Gene Model | MGI Sequence Detail 42620 C57BL/6J ±  kb
transcript NM_172608 RefSeq | MGI Sequence Detail 3388 C57BL/6  
polypeptide Q8BG09 UniProt | EBI | MGI Sequence Detail 407 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    387 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 87
    cDNA 87

    Microarray probesets 3
References
more
  • Summaries
    All 50
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 30
  • Earliest
    J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory