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Tmem184b Gene Detail
Summary
  • Symbol
    Tmem184b
  • Name
    transmembrane protein 184b
  • Synonyms
    4732495E13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445179
    NCBI Gene: 223693
  • Gene Overview
    MyGene.info: TMEM184B
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79360684-79403303 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445179
protein coding gene Chr15:79360684-79403569 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022073
protein coding gene Chr15:79620892-79667495 (-)
A/J MGP_AJ_G0022034
protein coding gene Chr15:76879520-76923273 (-)
AKR/J MGP_AKRJ_G0022009
protein coding gene Chr15:79024183-79070100 (-)
BALB/cJ MGP_BALBcJ_G0022040
protein coding gene Chr15:76871869-76916169 (-)
C3H/HeJ MGP_C3HHeJ_G0021811
protein coding gene Chr15:79019613-79063588 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022483
protein coding gene Chr15:82773230-82819370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020013
protein coding gene Chr15:73360923-73405151 (-)
CAST/EiJ MGP_CASTEiJ_G0021332
protein coding gene Chr15:79720719-79767770 (-)
CBA/J MGP_CBAJ_G0021776
protein coding gene Chr15:85332671-85380115 (-)
DBA/2J MGP_DBA2J_G0021905
protein coding gene Chr15:76362268-76405820 (-)
FVB/NJ MGP_FVBNJ_G0021883
protein coding gene Chr15:75393719-75437974 (-)
LP/J MGP_LPJ_G0021973
protein coding gene Chr15:79812281-79858772 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021903
protein coding gene Chr15:90456687-90501683 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022497
protein coding gene Chr15:79038004-79083115 (-)
PWK/PhJ MGP_PWKPhJ_G0021074
protein coding gene Chr15:76371332-76416428 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020911
protein coding gene Chr15:78849129-78898868 (-)
WSB/EiJ MGP_WSBEiJ_G0021384
protein coding gene Chr15:79420479-79468856 (-)



Homology
more
  • Human Ortholog
    TMEM184B, transmembrane protein 184B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM184B, transmembrane protein 184B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C22orf5, FM08, HS5O6A, HSPC256
  • Links
    NCBI Gene ID: 25829
    neXtProt AC: NX_Q9Y519
    UniProt: Q9Y519

  • Chr Location
    22q13.1; chr22:38216045-38273034 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene-trapped allele exhibit delayed axon degeneration following peripheral nerve injury, progressive structural abnormalities at neuromuscular synapses, swellings within sensory terminals, sensory-motor dysfunction, and abnormal autophagy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 223693 NCBI Gene Model | MGI Sequence Detail 42620 C57BL/6J ±  kb
    transcript NM_172608 RefSeq | MGI Sequence Detail 3388 C57BL/6  
    polypeptide Q8BG09 UniProt | EBI | MGI Sequence Detail 407 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 87
      cDNA 87

      Microarray probesets 3
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 3
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory