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Ppig Gene Detail
Summary
  • Symbol
    Ppig
  • Name
    peptidyl-prolyl isomerase G (cyclophilin G)
  • Synonyms
    B230312B02Rik, SRCyp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445173
    NCBI Gene: 228005
  • Alliance
    gene page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:69553152-69584356 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 40.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1112 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445173
 protein coding gene Chr2:69552889-69584356 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025803
 protein coding gene Chr2:69705799-69738327 (+)
A/J MGP_AJ_G0025780
 protein coding gene Chr2:67018743-67053967 (+)
AKR/J MGP_AKRJ_G0025749
 protein coding gene Chr2:68826492-68862052 (+)
BALB/cJ MGP_BALBcJ_G0025775
 protein coding gene Chr2:67183619-67215421 (+)
C3H/HeJ MGP_C3HHeJ_G0025535
 protein coding gene Chr2:69065681-69100581 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026222
 protein coding gene Chr2:71824544-71857745 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023625
 protein coding gene Chr2:64249352-64280799 (+)
CAST/EiJ MGP_CASTEiJ_G0024999
 protein coding gene Chr2:69178806-69213454 (+)
CBA/J MGP_CBAJ_G0025515
 protein coding gene Chr2:74458679-74501200 (+)
DBA/2J MGP_DBA2J_G0025646
 protein coding gene Chr2:66654142-66686506 (+)
FVB/NJ MGP_FVBNJ_G0025609
 protein coding gene Chr2:66036147-66067760 (+)
LP/J MGP_LPJ_G0025735
 protein coding gene Chr2:69559154-69593843 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025638
 protein coding gene Chr2:76507609-76563719 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026279
 protein coding gene Chr2:68930057-68961308 (+)
PWK/PhJ MGP_PWKPhJ_G0024740
 protein coding gene Chr2:66494373-66527749 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024547
 protein coding gene Chr2:69140925-69171100 (+)
WSB/EiJ MGP_WSBEiJ_G0025067
 protein coding gene Chr2:69346270-69380892 (+)



Homology
more
  • Human Ortholog
    PPIG, peptidylprolyl isomerase G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPIG, peptidylprolyl isomerase G
  • Synonyms
    CARS-Cyp, CYP, SCAF10, SRCyp
  • Links
    NCBI Gene ID: 9360
    UniProt: Q13427

  • Chr Location
    2q31.1; chr2:169584342-169641406 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    24
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    20
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 228005 NCBI Gene Model | MGI Sequence Detail 31205 C57BL/6J ±  kb
transcript NM_001407464 RefSeq | MGI Sequence Detail 6349 C57BL/6  
polypeptide A2AR02 UniProt | EBI | MGI Sequence Detail 752 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000013081 peptidyl-prolyl cis-trans isomerase G
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
  • GlyGen
    A2AR02 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 21
    Genomic 1
    cDNA 20

    Microarray probesets 7
References
more
  • Summaries
    All 40
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory