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Pisd
Gene Detail
 Symbol
Name
ID
Pisd
phosphatidylserine decarboxylase
MGI:2445114
Synonyms 9030221M09Rik
Feature Type protein coding gene
Genetic Map
Chromosome 5
17.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:32736301-32785646 bp, - strand
From VEGA annotation of GRCm38

  49346 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:81653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pisd

Human
homologs
Human Homolog PISD, phosphatidylserine decarboxylase
NCBI Gene ID 23761
neXtProt AC  NX_Q9UG56
Human Synonyms  DJ858B16, dJ858B16.2, PSD, PSDC, PSSC
Human Chr (Location)  22q12.2; chr22:31618491-31662564 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (ENU)(1) Gene trapped(2) Radiation induced(2) Targeted(1)
Genomic Mutations involving Pisd (3)
 
Mice homozygous for a null mutation in this gene display embryogenesis defects such as abnormal trophoblast development, abnormal extraembronic tissue morphology and abnormal mitochondrial morphology.
 
Alleles Annotated to Human Diseases(2)    Phenotype Images(2)
Interactions
Pisd interacts with 271 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process lipid metabolic process, phospholipid biosynthetic process
Component mitochondrion, nucleus
Function carboxy-lyase activity, lyase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (175)    Tissues (128)    Images (51)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 175
cDNA source data(124)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(126) cDNA(125) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021306 (Evidence)
Ensembl Gene ModelENSMUSG00000023452 (Evidence)
Entrez Gene320951 (Evidence)
UniGene273765
DoTSDT.99866187
EC4.1.1.65
Consensus CDS ProjectCCDS19194.1
International Mouse Knockout Project StatusPisd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021306 VEGA Gene Model | MGI Sequence Detail 49346 C57BL/6J ±  kb
transcript OTTMUST00000069281 VEGA | MGI Sequence Detail 2183 Not Applicable 
polypeptide OTTMUSP00000035165 VEGA | MGI Sequence Detail 406 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(10) UniProt(9)
Polymorphisms SNPs within 2kb(246 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005221 Phosphatidylserine decarboxylase
InterPro IPR003817 Phosphatidylserine decarboxylase-related
Protein Ontology PR:000012752 phosphatidylserine decarboxylase proenzyme
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:197464 Lagarrigue S, et al., Limited RNA editing in exons of mouse liver and adipose. Genetics. 2013 Apr;193(4):1107-15
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory