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Zdhhc17
Gene Detail
 Symbol
Name
ID
Zdhhc17
zinc finger, DHHC domain containing 17
MGI:2445110
Synonyms A230053P19Rik, D130071N24Rik, Hip14, mKIAA0946
Feature Type protein coding gene
Genetic Map
Chromosome 10
57.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:110941782-111010066 bp, - strand
From Ensembl annotation of GRCm38

  68285 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56324  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zdhhc17

Human
homologs
Human Homolog ZDHHC17, zinc finger, DHHC-type containing 17
NCBI Gene ID 23390
neXtProt AC  NX_Q8IUH5
Human Synonyms  HIP14, HIP3, HYPH
Human Chr (Location)  12q21.2; chr12:76764074-76853872 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit reminiscent of Huntington disease (decreased body weight, impaired coordination, hyperactivity, increased rearing, decreased prepulse inhibition, increased stereotypic behavior, reduced striatum, and decreased brain weight).
 
Human Diseases Modeled Using Mouse Zdhhc17 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Zdhhc17 interacts with 366 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process cation transmembrane transport, ion transport, ...
Component cytoplasm, cytoplasmic vesicle, ...
Function identical protein binding, magnesium ion transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (32)    Tissues (23)    Images (2)
Theiler Stages: 2, 3, 4, 5, 23, 28
Assay TypeResults
RNA in situ 24
RT-PCR 8
cDNA source data(84)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) cDNA(84) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000035798 (Evidence)
Entrez Gene320150 (Evidence)
UniGene339281
DFCITC1580170, TC1581310, TC1603265, TC1700658, TC1725045
DoTSDT.101376046, DT.101736086, DT.528879, DT.91552872
NIA Mouse Gene IndexU032220
EC2.3.1.225
Consensus CDS ProjectCCDS56748.1
International Mouse Knockout Project StatusZdhhc17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035798 Ensembl Gene Model | MGI Sequence Detail 68285 C57BL/6J ±  kb
transcript ENSMUST00000041723 Ensembl | MGI Sequence Detail 4546 Not Applicable 
polypeptide ENSMUSP00000043279 Ensembl | MGI Sequence Detail 632 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(758 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR001594 Zinc finger, DHHC-type, palmitoyltransferase
Protein Ontology PR:000017611 palmitoyltransferase ZDHHC17
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:205275 Milnerwood AJ, et al., Memory and synaptic deficits in Hip14/DHHC17 knockout mice. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20296-301
All references(41)
Disease annotation references (2)
Other
accession IDs
MGI:2143904, MGI:2443485

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory