Zdhhc17
Gene Detail

Symbol Name ID

Zdhhc17 zinc finger, DHHC domain containing 17 MGI:2445110

Synonyms

A230053P19Rik, D130071N24Rik, Hip14, mKIAA0946

Feature Type

protein coding gene

Genetic Map

Chromosome 10

57.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr10:110941782-111010066 bp, - strand From Ensembl annotation of GRCm38   68285 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56324  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Zdhhc17

Human homologs

Human Homolog		ZDHHC17, zinc finger, DHHC-type containing 17
NCBI Gene ID		23390
neXtProt AC		NX_Q8IUH5
Human Synonyms		HIP14, HIP3, HYPH
Human Chr (Location)		12q21.2; chr12:77157854-77247474 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(1) Gene trapped(4)
 

Mice homozygous for a knock-out allele exhibit reminiscent of Huntington disease (decreased body weight, impaired coordination, hyperactivity, increased rearing, decreased prepulse inhibition, increased stereotypic behavior, reduced striatum, and decreased brain weight).

 
Human Diseases Modeled Using Mouse Zdhhc17 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (23 annotations)

Process	ion transport, lipoprotein transport, ...
Component	cytoplasm, cytoplasmic vesicle, ...
Function	magnesium ion transmembrane transporter activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (39)    Tissues (28)    Images (2)
Theiler Stages: 2, 3, 4, 5, 23, 28

Assay Type	Results
RNA in situ	24
RT-PCR	15

cDNA source data(85)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(86) cDNA(85) Primer pair(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000035798 (Evidence)
Entrez Gene	320150 (Evidence)
UniGene	339281
DFCI	TC1580170, TC1581310, TC1603265, TC1700658, TC1725045
DoTS	DT.101376046, DT.101736086, DT.528879, DT.91552872
NIA Mouse Gene Index	U032220
EC	2.3.1.-
Consensus CDS Project	CCDS56748.1
International Mouse Knockout Project Status	Zdhhc17

Sequences

Length	Strain/Species
genomic	ENSMUSG00000035798	Ensembl Gene Model | MGI Sequence Detail	68285	C57BL/6J
transcript	ENSMUST00000041723	Ensembl | MGI Sequence Detail	4546	Not Applicable
polypeptide	ENSMUSP00000043279	Ensembl | MGI Sequence Detail	632	Not Applicable

All sequences(45) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(283 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002110	Ankyrin repeat
InterPro	IPR020683	Ankyrin repeat-containing domain
InterPro	IPR001594	Zinc finger, DHHC-type, palmitoyltransferase
Protein Ontology	PR:000017611	palmitoyltransferase ZDHHC17

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:191129 Sutton LM, et al., Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease. Hum Mol Genet. 2013 Feb 1;22(3):452-65
All references(40)

Other accession IDs

MGI:2143904, MGI:2443485