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Zdhhc17 Gene Detail
Summary
  • Symbol
    Zdhhc17
  • Name
    zinc finger, DHHC domain containing 17
  • Synonyms
    A230053P19Rik, D130071N24Rik, Hip14, mKIAA0946
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445110
    NCBI Gene: 320150
  • Gene Overview
    MyGene.info: ZDHHC17
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr10:110941779-111010066 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      68288 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 57.86 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZDHHC17, zinc finger DHHC-type containing 17
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZDHHC17, zinc finger DHHC-type containing 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DHHC-17, HIP14, HIP3, HSPC294, HYPH
  • Links
    NCBI Gene ID: 23390
    neXtProt AC: NX_Q8IUH5
    UniProt: Q8IUH5

  • Chr Location
    12q21.2; chr12:76764074-76853701 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Zdhhc17 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit reminiscent of Huntington disease (decreased body weight, impaired coordination, hyperactivity, increased rearing, decreased prepulse inhibition, increased stereotypic behavior, reduced striatum, and decreased brain weight).
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320150 NCBI Gene Model | MGI Sequence Detail 68288 C57BL/6J ±  kb
    transcript NM_172554 RefSeq | MGI Sequence Detail 4563 C57BL/6  
    polypeptide Q80TN5 UniProt | EBI | MGI Sequence Detail 632 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      753 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 89
      cDNA 87
      Primer pair 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2143904, MGI:2443485
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 5
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:258534 Skotte NH, et al., Palmitoylation of caspase-6 by HIP14 regulates its activation. Cell Death Differ. 2017 Mar;24(3):433-444

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    10/09/2018
    MGI 6.12
    The Jackson Laboratory