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Tbck Gene Detail
Summary
  • Symbol
    Tbck
  • Name
    TBC1 domain containing kinase
  • Synonyms
    1700120J03Rik, A630047E20Rik, C030007I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445052
    NCBI Gene: 271981
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:132684144-132841688 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 61.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    888 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445052
protein coding gene Chr3:132683992-132841688 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027893
protein coding gene Chr3:135458612-135625103 (+)
A/J MGP_AJ_G0027851
protein coding gene Chr3:130682184-130839998 (+)
AKR/J MGP_AKRJ_G0027816
protein coding gene Chr3:134096049-134251809 (+)
BALB/cJ MGP_BALBcJ_G0027864
protein coding gene Chr3:130514124-130670500 (+)
C3H/HeJ MGP_C3HHeJ_G0027593
protein coding gene Chr3:134487137-134643053 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028307
protein coding gene Chr3:140218105-140383424 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025645
protein coding gene Chr3:126122295-126271788 (+)
CAST/EiJ MGP_CASTEiJ_G0027049
protein coding gene Chr3:134233584-134394745 (+)
CBA/J MGP_CBAJ_G0027569
protein coding gene Chr3:144951724-145122990 (+)
DBA/2J MGP_DBA2J_G0027709
protein coding gene Chr3:129853243-130005168 (+)
FVB/NJ MGP_FVBNJ_G0027676
protein coding gene Chr3:127428745-127577355 (+)
LP/J MGP_LPJ_G0027819
protein coding gene Chr3:136944975-137104081 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027707
protein coding gene Chr3:152918874-153091631 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028365
protein coding gene Chr3:133759907-133921552 (+)
PWK/PhJ MGP_PWKPhJ_G0026773
protein coding gene Chr3:129612967-129772103 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026598
protein coding gene Chr3:131834214-131990533 (+)
WSB/EiJ MGP_WSBEiJ_G0027128
protein coding gene Chr3:134523030-134681134 (+)



Homology
more
  • Human Ortholog
    TBCK, TBC1 domain containing kinase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBCK, TBC1 domain containing kinase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HSPC302, IHPRF3, TBCKL
  • Links
    NCBI Gene ID: 93627
    neXtProt AC: NX_Q8TEA7
    UniProt: Q8TEA7

  • Chr Location
    4q24; chr4:106044317-106316704 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13221
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TBCK
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028030 Ensembl Gene Model | MGI Sequence Detail 157545 C57BL/6J ±  kb
transcript ENSMUST00000169172 Ensembl | MGI Sequence Detail 6578 Not Applicable  
polypeptide ENSMUSP00000129205 Ensembl | MGI Sequence Detail 893 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1921563, MGI:1924592
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory