About   Help   FAQ
Plppr1 Gene Detail
Summary
  • Symbol
    Plppr1
  • Name
    phospholipid phosphatase related 1
  • Synonyms
    E130309F12Rik, Lppr1, PRG-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445015
    NCBI Gene: 272031
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:49059273-49340259 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 26.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7791 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445015
 protein coding gene Chr4:49054986-49340261 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028278
 protein coding gene Chr4:47501166-47785911 (+)
A/J MGP_AJ_G0028238
 protein coding gene Chr4:45727425-45971552 (+)
AKR/J MGP_AKRJ_G0028187
 protein coding gene Chr4:46919416-47203947 (+)
BALB/cJ MGP_BALBcJ_G0028257
 protein coding gene Chr4:45863629-46123221 (+)
C3H/HeJ MGP_C3HHeJ_G0027978
 protein coding gene Chr4:47492133-47783842 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028698
 protein coding gene Chr4:49220177-49514183 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026007
 protein coding gene Chr4:43052335-43313509 (+)
CAST/EiJ MGP_CASTEiJ_G0027417
 protein coding gene Chr4:47078688-47388960 (+)
CBA/J MGP_CBAJ_G0027944
 protein coding gene Chr4:50814813-51181540 (+)
DBA/2J MGP_DBA2J_G0028094
 protein coding gene Chr4:45618968-45907728 (+)
FVB/NJ MGP_FVBNJ_G0028061
 protein coding gene Chr4:44892384-45177015 (+)
LP/J MGP_LPJ_G0028193
 protein coding gene Chr4:47580427-47949625 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028085
 protein coding gene Chr4:53810018-54159442 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028733
 protein coding gene Chr4:47101049-47405388 (+)
PWK/PhJ MGP_PWKPhJ_G0027142
 protein coding gene Chr4:45750646-46055330 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026970
 protein coding gene Chr4:46618632-46869355 (+)
WSB/EiJ MGP_WSBEiJ_G0027495
 protein coding gene Chr4:47041358-47330480 (+)



Homology
more
  • Human Ortholog
    PLPPR1, phospholipid phosphatase related 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPPR1, phospholipid phosphatase related 1
  • Synonyms
    LPPR1, PRG-3, PRG3
  • Links
    NCBI Gene ID: 54886
    UniProt: Q8TBJ4

  • Chr Location
    9q31.1; chr9:101028727-101325135 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    843
  • Tissues
    59
  • cDNA Data
    22
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063446 Ensembl Gene Model | MGI Sequence Detail 280987 C57BL/6J ±  kb
transcript ENSMUST00000076670 Ensembl | MGI Sequence Detail 3940 Not Applicable  
polypeptide ENSMUSP00000075966 Ensembl | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009903 phospholipid phosphatase-related protein type 1
    (term hierarchy)
  • InterPro Domains
    IPR043216 Phosphatidate (PA) phosphatase-related
    IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
    IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
  • GlyGen
    Q8BFZ2 3 sites
Molecular
Reagents
less
  • All nucleic 23
    cDNA 22
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:323226 Gross I, et al., Systematic expression analysis of plasticity-related genes in mouse brain development brings PRG4 into play. Dev Dyn. 2022 Apr;251(4):714-728
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory