Spg11
Gene Detail

Symbol Name ID

Spg11 spastic paraplegia 11 MGI:2444989

Synonyms

6030465E24Rik, C530005A01Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 2

60.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr2:122053520-122118386 bp, - strand From VEGA annotation of GRCm38   64867 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41614  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Spg11

Human homologs

Human Homolog		SPG11, spastic paraplegia 11 (autosomal recessive)
NCBI Gene ID		80208
neXtProt AC		NX_Q96JI7
Human Synonyms		KIAA1840
Human Chr (Location)		15q14; chr15:44854894-44955876 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SPG11

Alleles and phenotypes

All alleles(13) : Gene trapped(13)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	biological_process
Component	cytoplasm, cytoplasmic vesicle, ...
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(7)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000015533 (Evidence)
Ensembl Gene Model	ENSMUSG00000033396 (Evidence)
Entrez Gene	214585 (Evidence)
DFCI	TC1582070, TC1587405, TC1597276, TC1612109
Consensus CDS Project	CCDS50687.1
International Mouse Knockout Project Status	Spg11

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015533	VEGA Gene Model | MGI Sequence Detail	64867	C57BL/6J
transcript	OTTMUST00000036886	VEGA | MGI Sequence Detail	7671	Not Applicable
polypeptide	OTTMUSP00000016549	VEGA | MGI Sequence Detail	2430	Not Applicable

All sequences(31) RefSeq(3) UniProt(1)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000015517	spatacsin

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:177948 Murmu RP, et al., Cellular distribution and subcellular localization of spatacsin and spastizin, two proteins involved in hereditary spastic paraplegia. Mol Cell Neurosci. 2011 Jul;47(3):191-202
All references(29)

Other accession IDs

MGI:2443068