About   Help   FAQ
Phldb2 Gene Detail
Summary
  • Symbol
    Phldb2
  • Name
    pleckstrin homology like domain, family B, member 2
  • Synonyms
    C820004H04Rik, LL5b, LL5beta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444981
    NCBI Gene: 208177
  • Gene Overview
    MyGene.info: PHLDB2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:45746243-45953598 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 30.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1597 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444981
protein coding gene Chr16:45746230-45953702 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022859
protein coding gene Chr16:44538399-44759813 (-)
A/J MGP_AJ_G0022824
protein coding gene Chr16:42545938-42760877 (-)
AKR/J MGP_AKRJ_G0022796
protein coding gene Chr16:43946640-44157703 (-)
BALB/cJ MGP_BALBcJ_G0022825
protein coding gene Chr16:42571358-42780359 (-)
C3H/HeJ MGP_C3HHeJ_G0022589
protein coding gene Chr16:44104978-44314396 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023272
protein coding gene Chr16:45552225-45781350 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020786
protein coding gene Chr16:42902088-43113698 (-)
CAST/EiJ MGP_CASTEiJ_G0022114
protein coding gene Chr16:44298933-44519351 (-)
CBA/J MGP_CBAJ_G0022560
protein coding gene Chr16:47464074-47690392 (-)
DBA/2J MGP_DBA2J_G0022692
protein coding gene Chr16:42285002-42492986 (-)
FVB/NJ MGP_FVBNJ_G0022668
protein coding gene Chr16:42196860-42405156 (-)
LP/J MGP_LPJ_G0022760
protein coding gene Chr16:44271953-44512443 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022686
protein coding gene Chr16:46879334-47102245 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023287
protein coding gene Chr16:43959187-44177646 (-)
PWK/PhJ MGP_PWKPhJ_G0021854
protein coding gene Chr16:42653553-42866235 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021685
protein coding gene Chr16:43891958-44105796 (-)
WSB/EiJ MGP_WSBEiJ_G0022159
protein coding gene Chr16:44053648-44271014 (-)



Homology
more
  • Human Ortholog
    PHLDB2, pleckstrin homology like domain family B member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PHLDB2, pleckstrin homology like domain family B member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LL5b, LL5beta
  • Links
    NCBI Gene ID: 90102
    neXtProt AC: NX_Q86SQ0
    UniProt: Q86SQ0

  • Chr Location
    3q13.2; chr3:111732480-111976517 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033149 Ensembl Gene Model | MGI Sequence Detail 207356 C57BL/6J ±  kb
transcript ENSMUST00000076333 Ensembl | MGI Sequence Detail 5347 Not Applicable  
polypeptide ENSMUSP00000075672 Ensembl | MGI Sequence Detail 1302 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 73
    cDNA 73

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146603
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory