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Letm2 Gene Detail
Summary
  • Symbol
    Letm2
  • Name
    leucine zipper-EF-hand containing transmembrane protein 2
  • Synonyms
    D030041N04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444979
    NCBI Gene: 270035
Location & Maps
more
  • Sequence Map
    Chr8:25578492-25597487 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18996 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 14.17 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    LETM2, leucine zipper and EF-hand containing transmembrane protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LETM2, leucine zipper and EF-hand containing transmembrane protein 2
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 137994
    neXtProt AC: NX_Q2VYF4

  • Chr Location
    8p11.23; chr8:38386429-38409527 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 56358
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: LETM2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    4
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037363 Ensembl Gene Model | MGI Sequence Detail 18996 C57BL/6J ±  kb
transcript ENSMUST00000079160 Ensembl | MGI Sequence Detail 2098 Not Applicable  
polypeptide ENSMUSP00000078160 Ensembl | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    74 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031570 LETM1 domain-containing protein LETM2, mitochondrial
  • InterPro Domains
    IPR011685 LETM1-like
    IPR033122 Letm1 ribosome-binding domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 6
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory