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Rad54b
Gene Detail
Symbol

Name
ID
Rad54b
RAD54 homolog B (S. cerevisiae)
MGI:3605986
Synonyms
E130016E03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
5.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:11558922-11615805 bp, + strand
From VEGA annotation of GRCm38

  56884 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8240  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAD54B
Protein SuperFamily: DNA repair and recombination protein RAD54B
Gene Tree: Rad54b

Human
homologs
RAD54B, RAD54 homolog B (S. cerevisiae)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 25788
neXtProt AC: NX_O95073, NX_Q9Y620

Human Synonyms: RDH54

Human Chr (Location): 8q22.1; chr8:94371960-94475115 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RAD54B

Mutations,
alleles, and
phenotypes
All mutations/alleles(142) : Gene trapped(140) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene have an increased sensitivity to ionizing radiation and other agents of DNA damage but outherwise have a normal phenotype.
 
Interactions
Rad54b interacts with 311 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular response to DNA damage stimulus, determination of adult lifespan, ...
Component nucleus
Function DNA translocase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (92)    Tissues (92)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 92
cDNA source data(7)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase rad54b    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000004520 (Evidence)
Ensembl Gene Model ENSMUSG00000078773 (Evidence)
Entrez Gene 623474 (Evidence)
Consensus CDS Project CCDS17970.1, CCDS57262.1
International Mouse Phenotyping Consortium Status Rad54b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004520 VEGA Gene Model | MGI Sequence Detail 56884 C57BL/6J ±  kb
transcript OTTMUST00000010239 VEGA | MGI Sequence Detail 2870 Not Applicable 
polypeptide OTTMUSP00000004870 VEGA | MGI Sequence Detail 886 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(5)
Polymorphisms
SNPs within 2kb(273 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000013679 DNA repair and recombination protein RAD54B
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2444973

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory